PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21900690-6	2011	The JNK inhibitor SP600125 reduced ANG II-induced IRS-1 Ser307 phosphorylation (by 80%), IRS-1 Ser302 phosphorylation (by 70%), and IRS-1 Ser632 phosphorylation (by 50%).	pyrazolanthrone	18-26	insulin receptor substrate 1	Homo sapiens	50-55	
21900690-6	2011	The JNK inhibitor SP600125 reduced ANG II-induced IRS-1 Ser307 phosphorylation (by 80%), IRS-1 Ser302 phosphorylation (by 70%), and IRS-1 Ser632 phosphorylation (by 50%).	pyrazolanthrone	18-26	insulin receptor substrate 1	Homo sapiens	89-94	
21900690-6	2011	The JNK inhibitor SP600125 reduced ANG II-induced IRS-1 Ser307 phosphorylation (by 80%), IRS-1 Ser302 phosphorylation (by 70%), and IRS-1 Ser632 phosphorylation (by 50%).	pyrazolanthrone	18-26	insulin receptor substrate 1	Homo sapiens	89-94	
16099428-1	2005	In 3T3-L1 adipocytes, insulin or anisomycin stimulated phosphorylation of IRS-1 at Ser(307) and Ser(636/639), both of which were partially reduced by the mTOR inhibitor, rapamycin, or the JNK inhibitor, SP600125, and were further inhibited by a combination of them.	pyrazolanthrone	203-211	insulin receptor substrate 1	Homo sapiens	74-79	
21478152-7	2011	Inhibition of JNK (with JNK inhibitor SP600125 or using dominant-negative JNK) reduced serine 307 phosphorylation of IRS1.	pyrazolanthrone	38-46	insulin receptor substrate 1	Homo sapiens	117-121	
12409308-9	2003	SP600125, a JNK inhibitor, prevented PMA and TNFalpha-induced IRS1 Ser-307 phosphorylation.	pyrazolanthrone	0-8	insulin receptor substrate 1	Homo sapiens	62-66