PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23877009-9	2013	Exposure of PX-866 treated cells to sorafenib reduced p62 and LAMP2 levels, decreased the ratio of LC3 to LC3II, and reduced LC3-GFP vesicle levels.	Sorafenib	36-45	nucleoporin 62	Homo sapiens	54-57	
35469578-10	2022	AZD4547 increased LC3 II/I, Beclin1, and Toll-like receptor 4 proteins, and decreased P62 protein level in Huh7R cells significantly when given in combination with sorafenib.	Sorafenib	164-173	nucleoporin 62	Homo sapiens	86-89	
26416459-9	2015	Furthermore, treatment with sorafenib induces the interaction of RIPK1 with p62, as demonstrated by immunoprecipitation and a proximity ligation assay.	Sorafenib	28-37	nucleoporin 62	Homo sapiens	76-79	
26403645-4	2016	Upon exposure to ferroptosis-inducing compounds (e.g., erastin, sorafenib, and buthionine sulfoximine), p62 expression prevented NRF2 degradation and enhanced subsequent NRF2 nuclear accumulation through inactivation of Kelch-like ECH-associated protein 1.	Sorafenib	64-73	nucleoporin 62	Homo sapiens	104-107	
26403645-6	2016	Knockdown of p62, quinone oxidoreductase-1, heme oxygenase-1, and ferritin heavy chain-1 by RNA interference in HCC cells promoted ferroptosis in response to erastin and sorafenib.	Sorafenib	170-179	nucleoporin 62	Homo sapiens	13-16	
26416459-11	2015	In summary, the formation of Atg5-deficient autophagosomes in response to sorafenib promotes the interaction of p62 with RIPK leading to cell death by necroptosis.	Sorafenib	74-83	nucleoporin 62	Homo sapiens	112-115	
25712526-6	2015	Sorafenib activated autophagy in RCC cells (786-0 and A489 lines), evidenced by p62 degradation, Beclin-1/autophagy protein 5 (ATG-5) upregulation and light chain (LC)3B-I/-II conversion.	Sorafenib	0-9	nucleoporin 62	Homo sapiens	80-83	
26516583-9	2015	We also detected features of autophagy blockage, as the protein levels of LC3-II and p62 were affected by combined treatment with FTY720 and sorafenib.	Sorafenib	141-150	nucleoporin 62	Homo sapiens	85-88