PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33450239-6	2021	Knockdown of ATM and CSN2 can suppress the expression of Snail and increase sorafenib sensitivity of HCC/SR cells.	Sorafenib	76-85	ATM serine/threonine kinase	Homo sapiens	13-16	
22265862-0	2012	Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling.	Sorafenib	76-85	ATM serine/threonine kinase	Homo sapiens	12-41	
22265862-2	2012	Here, we show that blockade of ataxia telangiectasia mutated (ATM) improves the antitumor effects of sorafenib.	Sorafenib	101-110	ATM serine/threonine kinase	Homo sapiens	31-60	
22265862-2	2012	Here, we show that blockade of ataxia telangiectasia mutated (ATM) improves the antitumor effects of sorafenib.	Sorafenib	101-110	ATM serine/threonine kinase	Homo sapiens	62-65	
22265862-3	2012	When hepatoma cell lines HepG2 and PLC/PRF/5 were treated with sorafenib plus ATM small inhibitory RNAs, ATM inhibitor KU55933 or caffeine, Akt signaling was suppressed and the cytotoxic effects were significantly potentiated.	Sorafenib	63-72	ATM serine/threonine kinase	Homo sapiens	105-108	
22265862-4	2012	Moreover, ATM inhibition effectively suppressed the sorafenib-induced cell migration.	Sorafenib	52-61	ATM serine/threonine kinase	Homo sapiens	10-13	
22265862-5	2012	Taken together, manipulation of ATM activity might be a useful strategy for improving sorafenib treatment of HCC.	Sorafenib	86-95	ATM serine/threonine kinase	Homo sapiens	32-35