PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28246302-5 2017 Ectopic overexpression of Tbeta4 in hepatocellular carcinoma cells could significantly enhance sphere-forming capacities and infiltrating phenotypes in vitro, and promote growth of tumors refractory to the VEGFR multikinase inhibitor sorafenib in vivo Clinically, sorafenib failed to improve the progression-free survival in patients with Tbeta4-high hepatocellular carcinoma, indicating that Tbeta4 expression could be available as a surrogate marker of susceptibility to this drug. Sorafenib 234-243 thymosin beta 4 X-linked Homo sapiens 26-32 28246302-5 2017 Ectopic overexpression of Tbeta4 in hepatocellular carcinoma cells could significantly enhance sphere-forming capacities and infiltrating phenotypes in vitro, and promote growth of tumors refractory to the VEGFR multikinase inhibitor sorafenib in vivo Clinically, sorafenib failed to improve the progression-free survival in patients with Tbeta4-high hepatocellular carcinoma, indicating that Tbeta4 expression could be available as a surrogate marker of susceptibility to this drug. Sorafenib 264-273 thymosin beta 4 X-linked Homo sapiens 26-32