PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20230385-5	2010	RESULTS: There was heterogeneity in tumour responsiveness to sunitinib or sorafenib according to CAIX status; the mean shrinkage was -17% vs -25% for sunitinib-treated patients with high vs low tumour CAIX expression, compared to -13% vs +9% for sorafenib-treated patients (P interaction, 0.05).	Sorafenib	74-83	carbonic anhydrase 9	Homo sapiens	97-101	
35550167-0	2022	Epigenetic regulation of the DNMT1/MT1G/KLF4/CA9 axis synergizes the anticancer effects of sorafenib in hepatocellular carcinoma.	Sorafenib	91-100	carbonic anhydrase 9	Homo sapiens	45-48	
35550167-10	2022	Our collective data revealed that sorafenib exerts its anticancer effects through epigenetic regulation of the DNMT1/MT1G/KLF4/CA9 axis in HCC and the activation of MT1G might constitute a strategy for enhancing the effect of sorafenib to suppress HCC cells.	Sorafenib	34-43	carbonic anhydrase 9	Homo sapiens	127-130	
30190369-11	2019	Sorafenib + mFOLFOX increased plasma PlGF, VEGF-D, sVEGFR1, IL12p70, and CAIX and CD4+ and CD8+ effector T lymphocytes and decreased plasma sVEGFR2 and s-c-KIT and regulatory T cells (Tregs).	Sorafenib	0-9	carbonic anhydrase 9	Homo sapiens	73-77	
20845535-13	2010	Similarly, CAIX expression was associated with a significantly higher treatment response rate in patients with metastatic RCC who received sorafenib.	Sorafenib	139-148	carbonic anhydrase 9	Homo sapiens	11-15	
23141780-0	2013	Carbonic anhydrase IX as a potential biomarker of efficacy in metastatic clear-cell renal cell carcinoma patients receiving sorafenib or placebo: analysis from the treatment approaches in renal cancer global evaluation trial (TARGET).	Sorafenib	124-133	carbonic anhydrase 9	Homo sapiens	0-21	
23141780-1	2013	OBJECTIVE: Retrospective data analyses have suggested that carbonic anhydrase IX (CAIX) may have a predictive role in patients with metastatic clear cell renal cell carcinoma (ccRCC) receiving high dose interleukin-2 or sorafenib.	Sorafenib	220-229	carbonic anhydrase 9	Homo sapiens	59-80	
23141780-1	2013	OBJECTIVE: Retrospective data analyses have suggested that carbonic anhydrase IX (CAIX) may have a predictive role in patients with metastatic clear cell renal cell carcinoma (ccRCC) receiving high dose interleukin-2 or sorafenib.	Sorafenib	220-229	carbonic anhydrase 9	Homo sapiens	82-86