PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33358859-8 2021 Furthermore, DAZAP1 significantly reduced cellular sensitivity to sorafenib (SF), which had been proven to be an inducer of ferroptosis by targeting the system Xc- (composed of a light chain, xCT/SLC7A11, and a heavy chain, 4F2 heavy chain). Sorafenib 66-75 solute carrier family 3 member 2 Homo sapiens 224-227 33358859-8 2021 Furthermore, DAZAP1 significantly reduced cellular sensitivity to sorafenib (SF), which had been proven to be an inducer of ferroptosis by targeting the system Xc- (composed of a light chain, xCT/SLC7A11, and a heavy chain, 4F2 heavy chain). Sorafenib 77-79 solute carrier family 3 member 2 Homo sapiens 224-227 31053148-12 2019 Overexpressed SNHG1 contributes to sorafenib resistance by activating the Akt pathway via regulating SLC3A2. Sorafenib 35-44 solute carrier family 3 member 2 Homo sapiens 101-107 31053148-14 2019 Sorafenib induced translocation of miR-21 to the nucleus, where it promoted the expression of SNHG1, resulting in upregulation of SLC3A2, leading to the activation of Akt pathway. Sorafenib 0-9 solute carrier family 3 member 2 Homo sapiens 130-136