PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31259702-0	2018	The Transcription Factor Creb is Involved in Sorafenib-Inhibited Renal Cancer Cell Proliferation, Migration and Invasion.	Sorafenib	45-54	cAMP responsive element binding protein 1	Homo sapiens	25-29	
31259702-2	2018	Our study, therefore, explored the role of CREB in sorafenib- -inhibited cell proliferation, migration and invasion.	Sorafenib	51-60	cAMP responsive element binding protein 1	Homo sapiens	43-47	
31259702-8	2018	Moreover, addition of the recombinant plasmid pCI-neo/ CREB (PN) reversed the sorafenib-induced inhibition of cell proliferation, migration and invasion.	Sorafenib	78-87	cAMP responsive element binding protein 1	Homo sapiens	55-59	
31259702-9	2018	These results show that CREB is associated with the sorafenib-induced inhibition of proliferation, migration and invasion.	Sorafenib	52-61	cAMP responsive element binding protein 1	Homo sapiens	24-28	
28237700-0	2017	Prostaglandin E1 reduces the keratinocyte toxicity of sorafenib by maintaining signal transducer and activator of transcription 3 (STAT3) activity and enhancing the cAMP response element binding protein (CREB) activity.	Sorafenib	54-63	cAMP responsive element binding protein 1	Homo sapiens	165-202	
28237700-0	2017	Prostaglandin E1 reduces the keratinocyte toxicity of sorafenib by maintaining signal transducer and activator of transcription 3 (STAT3) activity and enhancing the cAMP response element binding protein (CREB) activity.	Sorafenib	54-63	cAMP responsive element binding protein 1	Homo sapiens	204-208	
28237700-10	2017	Collectively, these findings indicate that PGE1 blocks the inhibitory effects of sorafenib on cell growth by maintaining the activity of STAT3 and enhancing the CREB activity.	Sorafenib	81-90	cAMP responsive element binding protein 1	Homo sapiens	161-165