PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27154061-10	2016	Notably, ADRB2 signaling negatively regulated autophagy by disrupting Beclin1/VPS34/Atg14 complex in an Akt-dependent manner, leading to HIF1alpha stabilization, reprogramming of HCC cells glucose metabolism, and the acquisition of resistance to sorafenib.	Sorafenib	246-255	beclin 1, autophagy related	Mus musculus	70-77	
30272354-5	2018	In LM3 cells, capsaicin and sorafenib combination treatment achieved a markedly stronger induction of apoptosis by increasing caspase-3, Bax and poly(ADP-ribose) polymerase activity and inhibiting Bcl-2, and induction of autophagy by upregulating the levels of beclin-1 and LC3A/B II, enhancing P62 degradation.	Sorafenib	28-37	beclin 1, autophagy related	Mus musculus	261-269	
30057310-4	2018	Knockdown of BECN1 by shRNA inhibits ferroptosis induced by system Xc- inhibitors (e.g., erastin, sulfasalazine, and sorafenib), but not other ferroptosis inducers including RSL3, FIN56, and buthionine sulfoximine.	Sorafenib	117-126	beclin 1, autophagy related	Mus musculus	13-18