PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30717317-0	2019	MiR-122 Targets SerpinB3 and Is Involved in Sorafenib Resistance in Hepatocellular Carcinoma.	Sorafenib	44-53	microRNA 122	Homo sapiens	0-7	
34306419-5	2021	Higher miR-122 and miR-197 expression levels were observed in the LC tissues of sorafenib-sensitive patients.	Sorafenib	80-89	microRNA 122	Homo sapiens	7-14	
34306419-6	2021	ROC curves demonstrated that miR-122 and miR-197 are predictive markers for the therapeutic effect of sorafenib.	Sorafenib	102-111	microRNA 122	Homo sapiens	29-36	
34306419-10	2021	CONCLUSION: miR-122 and miR-197 expression levels can predict LC patient responses to sorafenib chemotherapy, and their levels increase after chemotherapy.	Sorafenib	86-95	microRNA 122	Homo sapiens	12-19	
34194500-0	2021	High HBV Load Weakens Predictive Effect of Serum miR-122 on Response to Sorafenib in Hepatocellular Carcinoma Patients.	Sorafenib	72-81	microRNA 122	Homo sapiens	49-56	
34194500-2	2021	The aim of the study was to explore the association of serum miR-122 with response to sorafenib in hepatitis B virus- (HBV-) related hepatocellular carcinoma (HCC) patients and to further reveal the effect of the virus load on such potential relationship.	Sorafenib	86-95	microRNA 122	Homo sapiens	61-68	
34194500-10	2021	Conclusion: Higher serum level of miR-122 at baseline was associated with a better response to sorafenib in HBV-related locally advanced HCC patients, and relatively high HBV load weakened such predictive effect mentioned above.	Sorafenib	95-104	microRNA 122	Homo sapiens	34-41	
30717317-4	2019	Here, we assessed the relationship between miR-122 and SerpinB3 and their influence on cell phenotype and sorafenib resistance in HCC.	Sorafenib	106-115	microRNA 122	Homo sapiens	43-50	
30717317-10	2019	Anti-miR-122 transfection increased cell viability in sorafenib-treated Huh-7 cells, while miR-122 overexpression increased sorafenib sensitivity in treated cells, but not in those overexpressing SerpinB3.	Sorafenib	54-63	microRNA 122	Homo sapiens	5-12	
30717317-10	2019	Anti-miR-122 transfection increased cell viability in sorafenib-treated Huh-7 cells, while miR-122 overexpression increased sorafenib sensitivity in treated cells, but not in those overexpressing SerpinB3.	Sorafenib	124-133	microRNA 122	Homo sapiens	91-98	
19726678-12	2009	More importantly, growth and clonogenic survival of miR-122-expressing HCC cells were significantly reduced upon treatment with sorafenib, a multi-kinase inhibitor clinically effective against HCC.	Sorafenib	128-137	microRNA 122	Homo sapiens	52-59	
26655273-3	2016	Our miRNA microarray data indicate that liver-specific miR-122 expression was significantly reduced in sorafenib-resistant cells.	Sorafenib	103-112	microRNA 122	Homo sapiens	55-62	
26655273-4	2016	Overexpression of miR-122 made drug-tolerant cells sensitive to sorafenib and induced apoptosis.	Sorafenib	64-73	microRNA 122	Homo sapiens	18-25	
26655273-8	2016	These results indicated that activation of IGF-1R by ectopic down-regulation of miR-122 counteracted the effects of sorafenib-induced apoptosis, thus conferring sorafenib resistance.	Sorafenib	116-125	microRNA 122	Homo sapiens	80-87	
26655273-8	2016	These results indicated that activation of IGF-1R by ectopic down-regulation of miR-122 counteracted the effects of sorafenib-induced apoptosis, thus conferring sorafenib resistance.	Sorafenib	161-170	microRNA 122	Homo sapiens	80-87	
26655273-10	2016	Our data imply that an intimate correlation between miR-122 and IGF-1R abnormal expression is a critical determinant of sorafenib tolerance.	Sorafenib	120-129	microRNA 122	Homo sapiens	52-59