PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28099144-7 2017 We also find that miR-199a-5p and let-7c increase the sensitivity of HCC cells to sorafenib. Sorafenib 82-91 microRNA let-7c Homo sapiens 34-40 28099144-8 2017 CONCLUSIONS: We report that miR-199a-5p and let-7c cooperatively and efficiently inhibit HCC cell migration and invasion by targeting the metastasis promoter MAP4K3 and MAP4K3-mediated drug sensitization, suggesting that the use of miRNAs and sorafenib in combination therapy may be a powerful approach to the treatment of HCC. Sorafenib 243-252 microRNA let-7c Homo sapiens 44-50 20347499-11 2010 Finally, expression of let-7c enhanced apoptosis of hepatoma cells upon exposure to sorafenib, which downregulates expression of another anti-apoptotic Bcl-2 protein, Mcl-1. Sorafenib 84-93 microRNA let-7c Homo sapiens 23-29