PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31330833-0 2019 ANGPT2 and NOS3 Polymorphisms and Clinical Outcome in Advanced Hepatocellular Carcinoma Patients Receiving Sorafenib. Sorafenib 107-116 angiopoietin 2 Homo sapiens 0-6 33102759-13 2020 Responder rate was 40% (2/5) in patients with high baseline ANG2 and FGF19 levels who received sorafenib. Sorafenib 95-104 angiopoietin 2 Homo sapiens 60-64 21233403-10 2011 When combined with sunitinib, sorafenib, bevacizumab, irinotecan, or docetaxel, Ang2 CovX-Bodies produced even greater efficacy (~80% TGI, P < 0.01). Sorafenib 30-39 angiopoietin 2 Homo sapiens 80-84 31330833-8 2019 Our results suggest that ANGPT2rs55633437 and NOS3 rs2070744 polymorphisms could identify a subset of HCC patients more resistant to sorafenib. Sorafenib 133-142 angiopoietin 2 Homo sapiens 25-31 26420960-4 2015 Studies based on patient cohorts identified the potential of blood levels of angiopoietin-2, hepatocyte growth factor, insulin-like growth factor-1, and transforming growth factor-beta1 for predicting sorafenib efficacy. Sorafenib 201-210 angiopoietin 2 Homo sapiens 77-91 27266362-5 2016 In the (90)Y/sorafenib arm, Ang-2 and PDGF decreased at 2 weeks and the remainder increased. Sorafenib 13-22 angiopoietin 2 Homo sapiens 28-33 30402928-7 2019 CONCLUSIONS: Predictions of overall survival and post-progression survival were possible by periodically measuring serum proangiogenic cytokines, especially angiopoietin-2, in patients with HCC treated with sorafenib. Sorafenib 207-216 angiopoietin 2 Homo sapiens 157-171 24374901-7 2014 Repeated measures linear modeling from 15 patients demonstrated increased Ang2 (P <= 0.05) and decreased sVEGFR2 (P <= 0.05) after exposure to sorafenib. Sorafenib 149-158 angiopoietin 2 Homo sapiens 74-78 24045661-8 2013 CONCLUSION: High expression of Ang-2 or more than cytokines in serum is associated with poor PFS and OS in HCC patients treated with sorafenib. Sorafenib 133-142 angiopoietin 2 Homo sapiens 31-36