PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35342408-0 2022 microRNA-106b-5p Promotes Cell Growth and Sensitizes Chemosensitivity to Sorafenib by Targeting the BTG3/Bcl-xL/p27 Signaling Pathway in Hepatocellular Carcinoma. Sorafenib 73-82 cyclin-dependent kinase inhibitor 1B Mus musculus 112-115 35342408-9 2022 Altogether, these data suggest that miR-106b-5p promotes cell proliferation and cell cycle and increases HCC cells" resistance to sorafenib through the BTG3/Bcl-xL/p27 signaling pathway. Sorafenib 130-139 cyclin-dependent kinase inhibitor 1B Mus musculus 164-167 24852430-6 2014 Notably, Tiam1 siRNA or sorafenib alone obviously increased p27 level, but reduced Mcl-1 and bcl-2 levels in xenografted nude mice, and their combinations reached the best effect. Sorafenib 24-33 cyclin-dependent kinase inhibitor 1B Mus musculus 60-63 21693435-7 2011 Inhibition of Raf kinases with either sorafenib or B-Raf small interfering RNA (siRNA) caused a mitogen-activated protein kinase-mediated downregulation of p27. Sorafenib 38-47 cyclin-dependent kinase inhibitor 1B Mus musculus 156-159 21693435-9 2011 Finally, theophylline-mediated increases in p27 and cyclin D1 were attenuated by sorafenib, which modulated Raf/MEK/ERK signaling. Sorafenib 81-90 cyclin-dependent kinase inhibitor 1B Mus musculus 44-47