PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24980819-2 2014 In BRAF mutant melanoma cells, Usp5 activity was suppressed by BRAF inhibitor (vemurafenib) in sensitive but not in acquired or intrinsically resistant cells. Vemurafenib 79-90 ubiquitin specific peptidase 5 (isopeptidase T) Mus musculus 31-35 24980819-3 2014 Usp5 knockdown overcame acquired vemurafenib resistance and sensitized BRAF and NRAS mutant melanoma cells to apoptosis initiated by MEK inhibitor, cytokines or DNA-damaging agents. Vemurafenib 33-44 ubiquitin specific peptidase 5 (isopeptidase T) Mus musculus 0-4