PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34971971-8	2022	Mechanistically, RNA-Seq analysis of the PDAC xenografts and patients-PBMCs revealed that Zol exerts radiosensitization by affecting Rac1 and Rho prenylation, thereby modulating DNA damage and radiation response signalling along with improved systemic immune cells activation.	Zoledronic Acid	90-93	Rac family small GTPase 1	Homo sapiens	133-137	
25595279-2	2015	In this study, we hypothesized that zoledronic acid inhibits ovarian cancer angiogenesis preventing Rac1 activation.	Zoledronic Acid	36-51	Rac family small GTPase 1	Homo sapiens	100-104	
25595279-5	2015	Furthermore, zoledronic acid inactivated Rac1 and decreased the levels of Pak1/p38/matrix metalloproteinase-2 in ovarian cancer cells.	Zoledronic Acid	13-28	Rac family small GTPase 1	Homo sapiens	41-45	
25595279-6	2015	In vivo, zoledronic acid reduced tumor growth, angiogenesis, and cell proliferation and inactivated Rac1 in both HeyA8-MDR and OVCAR-5 models.	Zoledronic Acid	9-24	Rac family small GTPase 1	Homo sapiens	100-104	
25393473-3	2014	ZOL-treated cells decreased a ratio of membrane to cytoplasmic fractions in RhoA, Cdc42 and Rab6 but less significantly Rac1 proteins, indicating that these proteins were possible targets for ZOL-induced actions.	Zoledronic Acid	0-3	Rac family small GTPase 1	Homo sapiens	120-124