PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25162011-7 2014 RA produced a significant reduction in UVB-induced expression of IL-6, IL-8, MCP-1, and TNF-alpha when applied at the same time as irradiation. rosmarinic acid 0-2 interleukin 6 Homo sapiens 65-69 34439757-6 2021 Additionally, the RA-RF significantly reduced ROS production, IL-6, IL-8, TNF-alpha, and COX-2. rosmarinic acid 18-20 interleukin 6 Homo sapiens 62-66 23488631-5 2013 A significant, more than 50% mean inhibition of PMA/I-induced IL-6 and IL-8 release was demonstrated for the volatile compounds 1,8-cineole, borneol, camphor, and thujone, but not for the nonvolatile rosmarinic acid when applied in concentrations representative of sage infusion. rosmarinic acid 200-215 interleukin 6 Homo sapiens 62-66 22726350-3 2012 ST, rosmarinic acid, pulegone, and 2alpha,3alpha,24-thrihydrooxylen-12en-28oic acid treatment of HMC-1 cells led to significant suppression of pro-inflammatory cytokines (IL-6, IL-8, and TNF-alpha) in a dose dependent manner. rosmarinic acid 4-19 interleukin 6 Homo sapiens 171-175 26694802-6 2016 RA significantly reduced the production of tumor necrosis factor-alpha, IL-1beta, and IL-6 on the TSLP-stimulated HMC-1 cells. rosmarinic acid 0-2 interleukin 6 Homo sapiens 86-90 27210890-7 2016 KEY FINDINGS: RA significantly inhibited poly(I:C)-induced expression of inflammatory cytokines including IL-1beta, IL-6, IL-8, CCL20, and TNF-alpha, and downregulated NF-kappaB signaling pathway in human keratinocytes. rosmarinic acid 14-16 interleukin 6 Homo sapiens 116-120 33461297-1 2021 Recent data have shown anti-inflammatory effects for trans-resveratrol (RSV) and rosmarinic acid (RA) in various immune-competent cell models through reduction of lipopolysaccharide (LPS)-induced interleukin 6 (IL-6) release. rosmarinic acid 81-96 interleukin 6 Homo sapiens 196-209 33461297-1 2021 Recent data have shown anti-inflammatory effects for trans-resveratrol (RSV) and rosmarinic acid (RA) in various immune-competent cell models through reduction of lipopolysaccharide (LPS)-induced interleukin 6 (IL-6) release. rosmarinic acid 81-96 interleukin 6 Homo sapiens 211-215 29318480-4 2018 The results indicated that rosmarinic acid reduced the expression of CD11b, a marker of microglia and macrophages, in the brain and dramatically inhibited the levels of inflammatory cytokines and mediators, such as TNFalpha, IL-6, IL-1beta, COX-2, and iNOS, in a dose-dependent manner both in vitro and in vivo. rosmarinic acid 27-42 interleukin 6 Homo sapiens 225-229 26056431-13 2015 As expected, RA inhibited proinflammatory cytokines and microRNAs related to inflammation, suggesting that RA may suppress the Warburg effect via an inflammatory pathway, such as that involving interleukin (IL)-6/signal transducer and activator of transcription-3 (STAT3). rosmarinic acid 13-15 interleukin 6 Homo sapiens 194-212 26056431-13 2015 As expected, RA inhibited proinflammatory cytokines and microRNAs related to inflammation, suggesting that RA may suppress the Warburg effect via an inflammatory pathway, such as that involving interleukin (IL)-6/signal transducer and activator of transcription-3 (STAT3). rosmarinic acid 107-109 interleukin 6 Homo sapiens 194-212