PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11695848-4	2001	The glucuronidation of SN-38 was catalysed by UGT1A1, UGT1A3, UGT1A6 and UGT1A9 as well as by liver microsomes.	Irinotecan	23-28	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	54-60	
11695848-10	2001	The UGT isoforms involved in SN-38 glucuronidation could be classified into two types: low-Km types such as UGT1A1 and UGT1A9, and high-Km types such as UGT1A3 and UGT1A6, in terms of affinity toward substrate.	Irinotecan	29-34	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	153-159	
11695848-16	2001	Although cholic acid derivatives strongly inhibited the activity of SN-38 glucuronidation by UGT1A3, the inhibition profile did not parallel that in liver microsomes.	Irinotecan	68-73	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	93-99	
10381366-3	1999	In this study, we examined the potential for each of the UGT1-encoded isoforms (UGT1A1 and UGT1A3 through UGT1A10) to glucuronidate SN-38.	Irinotecan	132-137	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	91-97