PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31888640-7 2019 RESULTS: Ticagrelor and clopidogrel can inhibit the degradation of IKBalpha and phosphorylation of p65, prevent p65 from entering the nucleus, reduce the production of TNFalpha, IL-1, IL-8, IL-6 and IL-2, and alleviate the decrease in cell viability, cell migration and angiogenesis, the changes of cell cycle and apoptosis induced by LPS. Ticagrelor 9-19 C-X-C motif chemokine ligand 8 Homo sapiens 184-188 30252571-11 2019 The concentration of IL-8 and IL-10 were decreased in patients with half and standard-dose ticagrelor group. Ticagrelor 91-101 C-X-C motif chemokine ligand 8 Homo sapiens 21-25 26515417-7 2015 In contrast to clopidogrel, ticagrelor also significantly reduced peak levels of IL-8 and growth colony-stimulating factor and increased peak levels of the anti-inflammatory cytokine IL-10. Ticagrelor 28-38 C-X-C motif chemokine ligand 8 Homo sapiens 81-85