PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32832010-2 2020 Here, we investigate whether direct NLRP3 inflammasome inhibition exerts additive effects on myocardial protection induced by the P2Y12 receptor antagonist Ticagrelor. Ticagrelor 156-166 NLR family, pyrin domain containing 3 Rattus norvegicus 36-41 33512659-0 2021 Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-kappaB/NLRP3 Pathway in Ischemic Stroke. Ticagrelor 81-91 NLR family, pyrin domain containing 3 Rattus norvegicus 161-166 33512659-2 2021 In this study, we investigated the protective efficiency of pretreatment of indobufen or aspirin combined with clopidogrel or ticagrelor (IACT) on cerebral ischemic injury via NF-kappaB/NLRP3 pathway. Ticagrelor 126-136 NLR family, pyrin domain containing 3 Rattus norvegicus 186-191 32832010-9 2020 Myocardial IR induced the NLRP3 inflammasome complex formation, which was attenuated by either INF pretreatment ex vivo, or by repeated oral treatment with Ticagrelor. Ticagrelor 156-166 NLR family, pyrin domain containing 3 Rattus norvegicus 26-31 27830382-4 2016 HYPOTHESIS: Ticagrelor and rosuvastatin have additive effects on myocardial adenosine levels, and therefore, on IS and post-reperfusion activation of the NLRP3-inflammasome. Ticagrelor 12-22 NLR family, pyrin domain containing 3 Rattus norvegicus 154-159