PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33078829-4	2021	We found that MC-LR administered to mice by oral gavage mainly accumulated in liver and induced the activation of the NLRP3 inflammasome and production of mature IL-1beta.	cyanoginosin LR	14-19	interleukin 1 alpha	Mus musculus	162-170	
33078829-6	2021	We also found that inhibition of NLRP3 in mice attenuated MC-LR-induced IL-1beta production, indicating an essential role for NLRP3 in MC-LR-induced liver inflammatory injury.	cyanoginosin LR	58-63	interleukin 1 alpha	Mus musculus	72-80	
33078829-6	2021	We also found that inhibition of NLRP3 in mice attenuated MC-LR-induced IL-1beta production, indicating an essential role for NLRP3 in MC-LR-induced liver inflammatory injury.	cyanoginosin LR	135-140	interleukin 1 alpha	Mus musculus	72-80	
33078829-8	2021	Taken together, our in vivo and in vitro findings suggest a model in which the NLRP3 inflammasome activation, a result of AKT-mediated hyperphosphorylation of FOXO1 through inhibition of PP2A, plays a key role in MC-LR-induced liver inflammatory injury via IL-1beta secretion and pyroptotic cell death.	cyanoginosin LR	213-218	interleukin 1 alpha	Mus musculus	257-265	
32687983-4	2020	Cytokines and chemokines such as CD68, IL1beta, MCP-1, and TNF-alpha, as well as alpha-SMA were increased in the groups that were exposed to MC-LR with the high-fat diet compared to the vehicle group.	cyanoginosin LR	141-146	interleukin 1 alpha	Mus musculus	39-46