PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28852731-7	2016	RESULTS: Sal B significantly improved heart function and decreased infarct size; remarkably decreased levels of serum TNF-alpha and IL-Iotabeta levels, increased contents of myocardium antioxidant enzymes activities; western blot results showed that Sal B ameliorate the increased Bax and caspase-3 protins expressions and decreased Bcl-2 proteins expression and ratios of Bcl-2 to Bax.	salvianolic acid B	9-14	caspase 3	Rattus norvegicus	289-298	
22568239-5	2012	Meanwhile, Sal B has an effect on significantly reducing the expression of inhibit glutamate-induced active Caspase-3 protein, inhibiting accumulated glutamate-induced ROS and decreasing PC12 cell apoptosis rate within the range from 50 micromol x L(-1) to 200 micromol x L(-1).	salvianolic acid B	11-16	caspase 3	Rattus norvegicus	108-117	
25654620-10	2015	In particular, Sal-B inhibited HIF1alpha, BNIP3, and cleavage caspase 3 expression levels, thereby suppressing apoptosis.	salvianolic acid B	15-20	caspase 3	Rattus norvegicus	62-71	
23201927-5	2013	With MTT cell viability assay, LDH release, ROS generation, caspase-3 activity assay and Hoechst 33342/PI staining, we found that Sal B pretreatment provided significantly protection against ATO-induced cell death.	salvianolic acid B	130-135	caspase 3	Rattus norvegicus	60-69	
22876447-7	2012	SalB was found to inhibit the reduction in MMP and decrease the activation of caspase-3.	salvianolic acid B	0-4	caspase 3	Rattus norvegicus	78-87	
22876447-8	2012	CONCLUSION: 0.1, 1 and 10 mg/L of SalB inhibits activation of caspase-3 and early apoptosis of rat BMSCs induced by hypoxia/SD and could therefore enhance the survival rate of grafted stem cells.	salvianolic acid B	34-38	caspase 3	Rattus norvegicus	62-71	
27127491-5	2016	The amount of myelin sheath and the number of regenerating axons increased, neurological function recovered, and caspase-3 expression was decreased in the spinal cord of salvianolic acid B-treated animals compared with untreated control rats.	salvianolic acid B	170-188	caspase 3	Rattus norvegicus	113-122	
22568239-6	2012	CONCLUSION: The study proves that Sal B prevented against glutamate-induced cell injury via inhibiting ROS formation and Caspase-3 pathway-dependent apoptosis in PC12 cells.	salvianolic acid B	34-39	caspase 3	Rattus norvegicus	121-130	
28800882-5	2017	Preincubation with Sal B led to a significant decrease of caspase-9 and caspase-3 activity and poly ADP-ribose polymerase (PARP) cleavage.	salvianolic acid B	19-24	caspase 3	Rattus norvegicus	72-81	
34636119-9	2022	The pharmacology network results showed that Sal B and its metabolites could regulate ALB, PLG, ACE, CASP3, MMP9, MMP2, MTOR, etc.	salvianolic acid B	45-50	caspase 3	Rattus norvegicus	101-106	
29257241-4	2018	Salvianolic acid B was identified to recover cognitive deficits and neurocytes, reduce inflammation, oxidative stress and neurocyte apoptosis (caspase-3 and Bax protein expression) in cerebral small vessel disease rats.	salvianolic acid B	0-18	caspase 3	Rattus norvegicus	143-152