PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31837261-3	2019	This study aimed to investigate the effect of orientin on proliferation and apoptosis of T24 human transitional cell bladder carcinoma cells in vitro in the presence of an agonist and an inhibitor of nuclear factor-kappaB (NF-kappaB).	orientin	46-54	nuclear factor kappa B subunit 1	Homo sapiens	223-232	
31837261-4	2019	MATERIAL AND METHODS T24 cells were cultured and divided into four study groups: an untreated control group; a group treated with 100 muM orientin; a group treated with 100 muM orientin with NF-kappaB agonist, phorbol 12-myristate 13-acetate (PMA); and a group treated with 100 muM orientin and the NF-kappaB inhibitor, IkappaBalpha.	orientin	177-185	nuclear factor kappa B subunit 1	Homo sapiens	191-200	
31837261-4	2019	MATERIAL AND METHODS T24 cells were cultured and divided into four study groups: an untreated control group; a group treated with 100 muM orientin; a group treated with 100 muM orientin with NF-kappaB agonist, phorbol 12-myristate 13-acetate (PMA); and a group treated with 100 muM orientin and the NF-kappaB inhibitor, IkappaBalpha.	orientin	177-185	nuclear factor kappa B subunit 1	Homo sapiens	299-308	
31837261-4	2019	MATERIAL AND METHODS T24 cells were cultured and divided into four study groups: an untreated control group; a group treated with 100 muM orientin; a group treated with 100 muM orientin with NF-kappaB agonist, phorbol 12-myristate 13-acetate (PMA); and a group treated with 100 muM orientin and the NF-kappaB inhibitor, IkappaBalpha.	orientin	177-185	nuclear factor kappa B subunit 1	Homo sapiens	191-200	
31837261-4	2019	MATERIAL AND METHODS T24 cells were cultured and divided into four study groups: an untreated control group; a group treated with 100 muM orientin; a group treated with 100 muM orientin with NF-kappaB agonist, phorbol 12-myristate 13-acetate (PMA); and a group treated with 100 muM orientin and the NF-kappaB inhibitor, IkappaBalpha.	orientin	177-185	nuclear factor kappa B subunit 1	Homo sapiens	299-308	
31837261-8	2019	Treatment of T24 cells with orientin inhibited the expression of NF-kappaB and components of the Hedgehog signaling pathway, and the NF-kappaB agonist, PMA, reversed these effects.	orientin	28-36	nuclear factor kappa B subunit 1	Homo sapiens	65-74	
31837261-9	2019	CONCLUSIONS Treatment of T24 human bladder carcinoma cells in vitro with orientin inhibited cell proliferation and promoted cell apoptosis by suppressing the Hedgehog signaling pathway and NF-kappaB.	orientin	73-81	nuclear factor kappa B subunit 1	Homo sapiens	189-198