PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23220614-5	2013	ISO significantly inhibited the levels of ERK1/2 kinase and increased the expression of JNK and p38 kinases.	homoorientin	0-3	mitogen-activated protein kinase 1	Homo sapiens	96-99	
32626938-10	2020	In addition, ISO increased the expression levels of p-p38, p-JNK and IkappaB-alpha; and decreased the expression levels of p-extracellular signal-regulated kinase (ERK), p-signal transducer and activator of transcription (STAT)3, p-nuclear factor (NF)-kappaB, NF-kappaB and p-IkappaB; these effects were induced by mitogen-activated protein kinase (MAPK) inhibitors and blocked by NAC.	homoorientin	13-16	mitogen-activated protein kinase 1	Homo sapiens	123-162	
32626938-10	2020	In addition, ISO increased the expression levels of p-p38, p-JNK and IkappaB-alpha; and decreased the expression levels of p-extracellular signal-regulated kinase (ERK), p-signal transducer and activator of transcription (STAT)3, p-nuclear factor (NF)-kappaB, NF-kappaB and p-IkappaB; these effects were induced by mitogen-activated protein kinase (MAPK) inhibitors and blocked by NAC.	homoorientin	13-16	mitogen-activated protein kinase 1	Homo sapiens	164-167	
33232417-7	2020	IOT significantly increased the phosphorylation of AMPK, ERK, GSK3beta, JNK, PI3K and AKT.	homoorientin	0-3	mitogen-activated protein kinase 1	Homo sapiens	57-60