PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18593940-0 2008 Functional genomics identifies ABCC3 as a mediator of taxane resistance in HER2-amplified breast cancer. taxane 54-60 ATP binding cassette subfamily C member 3 Homo sapiens 31-36 18593940-7 2008 We also show that amplification of ABCC3 is present in primary breast tumors and that it occurs predominantly in HER2-amplified and luminal tumors, and we report on development of a specific fluorescence in situ hybridization assay that may have utility as a predictive biomarker of taxane resistance in breast cancer. taxane 283-289 ATP binding cassette subfamily C member 3 Homo sapiens 35-40