PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30944389-6 2019 A mechanistic study revealed that GlcN inhibited the expression of NLRP3 and IL-1beta precursor by reducing reactive oxygen species generation and NF-kappaB activation in lipopolysaccharide-activated macrophages. Glucosamine 34-38 NLR family pyrin domain containing 3 Homo sapiens 67-72 30944389-7 2019 GlcN also suppressed mitochondrial reactive oxygen species generation and mitochondrial integrity loss in NLRP3-activated macrophages. Glucosamine 0-4 NLR family pyrin domain containing 3 Homo sapiens 106-111 30944389-8 2019 Additionally, GlcN disrupted NLRP3 inflammasome assembly by inhibiting NLRP3 binding to PKR, NEK7 and ASC. Glucosamine 14-18 NLR family pyrin domain containing 3 Homo sapiens 29-34 30944389-8 2019 Additionally, GlcN disrupted NLRP3 inflammasome assembly by inhibiting NLRP3 binding to PKR, NEK7 and ASC. Glucosamine 14-18 NLR family pyrin domain containing 3 Homo sapiens 71-76