PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27380043-8	2017	In addition, TMP could notably down-regulate the characteristic proteins in Rho/ROCK signaling pathway such as RhoA and Rac1, which triggered abnormal changes of eNOS and ROS, respectively.	tetramethylpyrazine	13-16	nitric oxide synthase 3	Homo sapiens	162-166	
10946853-4	2000	Furthermore, TMPZ concentration (50 and 200 microM)- and time (15 and 30 min)-dependently triggered endothelial-type constitutive nitric oxide synthase (ecNOS) protein expression in human platelets.	tetramethylpyrazine	13-17	nitric oxide synthase 3	Homo sapiens	100-151	
10946853-4	2000	Furthermore, TMPZ concentration (50 and 200 microM)- and time (15 and 30 min)-dependently triggered endothelial-type constitutive nitric oxide synthase (ecNOS) protein expression in human platelets.	tetramethylpyrazine	13-17	nitric oxide synthase 3	Homo sapiens	153-158	
10946853-5	2000	These results indicated that TMPZ at micromolar concentrations stimulated nitric oxide production in human platelets via a novel mechanism that activated ecNOS protein expression.	tetramethylpyrazine	29-33	nitric oxide synthase 3	Homo sapiens	154-159