PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35498163-1	2022	Objective: To study structure-specific solubilization effect of Sulfobutyl ether-beta-cyclodextrin (SBE-beta-CD) on Remdesivir (RDV) and to understand the experimental clathration with the aid of quantum mechanics (QM), molecular docking and molecular dynamics (MD) calculations.	remdesivir	116-126	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	104-111	
35498163-1	2022	Objective: To study structure-specific solubilization effect of Sulfobutyl ether-beta-cyclodextrin (SBE-beta-CD) on Remdesivir (RDV) and to understand the experimental clathration with the aid of quantum mechanics (QM), molecular docking and molecular dynamics (MD) calculations.	remdesivir	128-131	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	104-111	
35498163-4	2022	Results: The phase solubility and solubilization effect of RDV in SBE-beta-CD were explored kinetically and thermodynamically for each assessed condition.	remdesivir	59-62	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	70-77	
35498163-5	2022	An optimal drug / SBE-beta-CD feeding molar ratio was determined stoichiometrically for RDV solubility in pH1.7 solution.	remdesivir	88-91	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	22-29	
35498163-7	2022	A possible hypothesis was raised to elucidate the experimentally observed stabilization of supersaturation based on the proposed RDV Cation A /SBE-beta-CD pocket conformations.	remdesivir	129-132	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	147-154	
35498163-8	2022	Conclusion: The computational explorations conformed to the experimentally determined phase solubilization and well elucidated the mechanism of macroscopic clathration between RDV and SBE-beta-CD from the perspective of microscopic molecular calculations.	remdesivir	176-179	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	188-195