PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34093539-0	2021	Remdesivir Alleviates Acute Kidney Injury by Inhibiting the Activation of NLRP3 Inflammasome.	remdesivir	0-10	NLR family pyrin domain containing 3	Homo sapiens	74-79	
34093539-3	2021	Here, we firstly reported that remdesivir (RDV, GS-5734), a broad-spectrum antiviral nucleotide prodrug, alleviated AKI by specifically inhibiting NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome activation in macrophages.	remdesivir	31-41	NLR family pyrin domain containing 3	Homo sapiens	147-196	
34093539-3	2021	Here, we firstly reported that remdesivir (RDV, GS-5734), a broad-spectrum antiviral nucleotide prodrug, alleviated AKI by specifically inhibiting NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome activation in macrophages.	remdesivir	31-41	NLR family pyrin domain containing 3	Homo sapiens	198-203	
34093539-3	2021	Here, we firstly reported that remdesivir (RDV, GS-5734), a broad-spectrum antiviral nucleotide prodrug, alleviated AKI by specifically inhibiting NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome activation in macrophages.	remdesivir	43-46	NLR family pyrin domain containing 3	Homo sapiens	147-196	
34093539-3	2021	Here, we firstly reported that remdesivir (RDV, GS-5734), a broad-spectrum antiviral nucleotide prodrug, alleviated AKI by specifically inhibiting NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome activation in macrophages.	remdesivir	43-46	NLR family pyrin domain containing 3	Homo sapiens	198-203	
34093539-3	2021	Here, we firstly reported that remdesivir (RDV, GS-5734), a broad-spectrum antiviral nucleotide prodrug, alleviated AKI by specifically inhibiting NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome activation in macrophages.	remdesivir	48-55	NLR family pyrin domain containing 3	Homo sapiens	147-196	
34093539-3	2021	Here, we firstly reported that remdesivir (RDV, GS-5734), a broad-spectrum antiviral nucleotide prodrug, alleviated AKI by specifically inhibiting NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome activation in macrophages.	remdesivir	48-55	NLR family pyrin domain containing 3	Homo sapiens	198-203	
34093539-4	2021	Mechanically, RDV effectively suppressed the activities of nuclear transcription factor (NF)-kappaB, mitogen-activated protein kinase (MAPK), which further led to the reduction of the inflammasome genes of NLRP3 transcription, limiting the activation of NLRP3 inflammasome in vivo and in vitro.	remdesivir	14-17	NLR family pyrin domain containing 3	Homo sapiens	206-211	
34093539-4	2021	Mechanically, RDV effectively suppressed the activities of nuclear transcription factor (NF)-kappaB, mitogen-activated protein kinase (MAPK), which further led to the reduction of the inflammasome genes of NLRP3 transcription, limiting the activation of NLRP3 inflammasome in vivo and in vitro.	remdesivir	14-17	NLR family pyrin domain containing 3	Homo sapiens	254-259