PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24909904-9	2014	Compared with those in TAA group, celecoxib significantly downregulated the hepatic expressions of TNF-alpha, IL-6, COX-2, PGE2 , MMP-2, MMP-9, TGF-beta1, Phospho-Smad2/3, Snail1, alpha-SMA, FSP-1, and vimentin while greatly restoring the levels of E-cadherin.	Celecoxib	34-43	transforming growth factor, beta 1	Rattus norvegicus	144-153	
30658157-5	2019	Celecoxib also reversed the CSA-evoked (i) reductions in the tubular and glomerular protein expression of CSE and levels of H2S, prostaglandin E2 (PGE2), and total antioxidant capacity (TAC), and (ii) increases in inflammatory (tumor necrosis factor-alpha, TNF-alpha), fibrotic (transforming growth factor-beta1, TGF-beta1) and apoptotic (caspase-3) cytokines.	Celecoxib	0-9	transforming growth factor, beta 1	Rattus norvegicus	279-311	
30658157-5	2019	Celecoxib also reversed the CSA-evoked (i) reductions in the tubular and glomerular protein expression of CSE and levels of H2S, prostaglandin E2 (PGE2), and total antioxidant capacity (TAC), and (ii) increases in inflammatory (tumor necrosis factor-alpha, TNF-alpha), fibrotic (transforming growth factor-beta1, TGF-beta1) and apoptotic (caspase-3) cytokines.	Celecoxib	0-9	transforming growth factor, beta 1	Rattus norvegicus	313-322	
24909904-12	2014	The inhibitory effect of celecoxib on the EMT of hepatocytes is associated with reduction of intrahepatic inflammation, preservation of normal basement matrix, and inhibition of TGF-beta1/Smad pathway.	Celecoxib	25-34	transforming growth factor, beta 1	Rattus norvegicus	178-187	
19201774-14	2009	Celecoxib treatment significantly decreased mRNA expression of COX-2, alpha-SMA, transforming growth factor beta1 (TGFbeta1) and collagen alpha1(I) in both models.	Celecoxib	0-9	transforming growth factor, beta 1	Rattus norvegicus	81-113	
24462674-0	2014	Celecoxib offsets the negative renal influences of cyclosporine via modulation of the TGF-beta1/IL-2/COX-2/endothelin ET(B) receptor cascade.	Celecoxib	0-9	transforming growth factor, beta 1	Rattus norvegicus	86-95	
24462674-8	2014	Together, the data suggest that the facilitation of the interplay between the TGF-beta1/IL-2/COX-2 pathway and the endothelin ET(B) receptors constitutes the cellular mechanism by which celecoxib ameliorates the nephrotoxic manifestations of CSA in rats.	Celecoxib	186-195	transforming growth factor, beta 1	Rattus norvegicus	78-87	
19201774-14	2009	Celecoxib treatment significantly decreased mRNA expression of COX-2, alpha-SMA, transforming growth factor beta1 (TGFbeta1) and collagen alpha1(I) in both models.	Celecoxib	0-9	transforming growth factor, beta 1	Rattus norvegicus	115-123	
19194550-8	2009	Celecoxib significantly recovered the expressions of nephrin, CD2AP, COX-2, and TGF-beta.	Celecoxib	0-9	transforming growth factor, beta 1	Rattus norvegicus	80-88	
17543298-10	2007	The Celecoxib administration also decreased the expression of TGFbeta(1), alpha-SMA and the labeling index of apoptotic cells in the smooth muscle layer of ligated ureters in the treated group.	Celecoxib	4-13	transforming growth factor, beta 1	Rattus norvegicus	62-72