PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23595625-7 2013 Furthermore, treatment of 4T1 tumor-bearing mice with the cyclooxygenase-2 inhibitor celecoxib or genetic disruption of cyclooxygenase-2 in 4T1 cells inhibits the inflammatory chemokines and infiltration of CD11b(+)Gr1(+) myeloid cells in the premetastatic brain and subsequent formation of brain metastasis. Celecoxib 85-94 integrin subunit alpha M Homo sapiens 207-212 17178380-3 2007 We report herein that administration of the selective COX-2 inhibitor, celecoxib, significantly reduces the number of Gr1(+)CD11b(+) immature myeloid suppressor cells (IMSCs) during chemoprevention of 1,2-dimethylhydrazine diHCl-(1,2-DMH-) induction of large intestinal tumors in Swiss mice. Celecoxib 71-80 integrin subunit alpha M Homo sapiens 124-129