PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16454695-8 2006 BSO, MK-571, celecoxib, or diclofenac sensitised MRP4/HepG2 cells to TPT cytotoxicity and partially reversed MRP4-mediated resistance to TPT. Celecoxib 13-22 ATP binding cassette subfamily C member 4 Homo sapiens 49-53 26141932-7 2016 DAMI cells treated with celecoxib, diclofenac, and naproxen showed a significant increase in MRP4-mRNA expression compared to the mock culture. Celecoxib 24-33 ATP binding cassette subfamily C member 4 Homo sapiens 93-97 17878487-0 2007 Celecoxib induces MRP-4 in lung cancer cells: therapeutic implications. Celecoxib 0-9 ATP binding cassette subfamily C member 4 Homo sapiens 18-23 17005917-10 2007 Phenylbutazone stimulated MRP2 and celecoxib MRP4 transport at low concentrations and inhibited both transporters at high concentration. Celecoxib 35-44 ATP binding cassette subfamily C member 4 Homo sapiens 45-49 16454695-10 2006 Preincubation of MRP4/HepG2 cells with BSO (200 microM) for 24 hr, celecoxib (50 microM), or MK-571 (100 microM) for 2 hr significantly increased the accumulation of TPT over 10 min in MRP4/HepG2 cells by 28.0%, 37.3% and 32.5% (P < 0.05), respectively. Celecoxib 67-76 ATP binding cassette subfamily C member 4 Homo sapiens 17-21 16454695-10 2006 Preincubation of MRP4/HepG2 cells with BSO (200 microM) for 24 hr, celecoxib (50 microM), or MK-571 (100 microM) for 2 hr significantly increased the accumulation of TPT over 10 min in MRP4/HepG2 cells by 28.0%, 37.3% and 32.5% (P < 0.05), respectively. Celecoxib 67-76 ATP binding cassette subfamily C member 4 Homo sapiens 185-189 18690847-3 2008 The aim of the study was to investigate the induction by celecoxib of some multidrug resistance proteins, MRP1, MRP2, MRP4 and MRP5, involved in the transport of irinotecan and 5-FU. Celecoxib 57-66 ATP binding cassette subfamily C member 4 Homo sapiens 118-122 18690847-8 2008 In both cell lines celecoxib induced MRP4 and MRP5 over-expression at RNA and protein levels. Celecoxib 19-28 ATP binding cassette subfamily C member 4 Homo sapiens 37-41 18690847-10 2008 Cryoimmunoelectron microscopy showed increased MRP4 and MRP5 immunolabeling in celecoxib treated cells both at cytoplasmic level and along the plasma membrane. Celecoxib 79-88 ATP binding cassette subfamily C member 4 Homo sapiens 47-51 16454695-8 2006 BSO, MK-571, celecoxib, or diclofenac sensitised MRP4/HepG2 cells to TPT cytotoxicity and partially reversed MRP4-mediated resistance to TPT. Celecoxib 13-22 ATP binding cassette subfamily C member 4 Homo sapiens 109-113 16132345-11 2005 The resistance of MRP4 to various CPTs tested was significantly reversed in the presence of dl-buthionine-(S,R)-sulfoximine (BSO, a gamma-glutamylcysteine synthetase inhibitor), MK571, celecoxib, or diclofenac (all MRP4 inhibitors). Celecoxib 185-194 ATP binding cassette subfamily C member 4 Homo sapiens 18-22 16132345-12 2005 In addition, the accumulation of CPT-11 and SN-38 over 120 min in MRP4/HepG2 cells was significantly reduced compared to V/HepG2 cells, whereas the addition of celecoxib, MK571, or BSO significantly increased their accumulation in MRP4/HepG2 cells. Celecoxib 160-169 ATP binding cassette subfamily C member 4 Homo sapiens 231-235