PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23857431-0	2014	Sulindac and Celecoxib regulate cell cycle progression by p53/p21 up regulation to induce apoptosis during initial stages of experimental colorectal cancer.	Celecoxib	13-22	KRAS proto-oncogene, GTPase	Rattus norvegicus	62-65	
23857431-10	2014	We may conclude that Sulindac and Celecoxib could possibly follow p53/p21 mediated regulation of cell proliferation, where down regulation of NF-kappaB signaling and activation of PPARgamma might serve as important additional events in vivo.	Celecoxib	34-43	KRAS proto-oncogene, GTPase	Rattus norvegicus	70-73	
16426843-0	2006	Celecoxib leads to G2/M arrest by induction of p21 and down-regulation of cyclin B1 expression in a p53-independent manner.	Celecoxib	0-9	KRAS proto-oncogene, GTPase	Rattus norvegicus	47-50	
19826045-10	2009	Rats that were fed the high-dose CP-31398 or a combination of low-dose CP-31398 and celecoxib showed considerable enhancement of p53 and p21(WAF1/CIP) expression, apoptosis, and reduced tumor cell proliferation in colonic tumors.	Celecoxib	84-93	KRAS proto-oncogene, GTPase	Rattus norvegicus	137-140	
12960143-11	2003	celecoxib induces cell cycle arrest at the G(1)-S phase transition point and modifies cell cycle regulatory proteins such as cyclin D1, retinoblastoma (Rb), and phosphorylated Rb, cyclin E, p27(KIP1), and p21(WAF1/CIP1).	Celecoxib	0-9	KRAS proto-oncogene, GTPase	Rattus norvegicus	205-208