PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29763644-0 2018 Immunomodulatory effect of Celecoxib on HMGB1/TLR4 pathway in a recurrent seizures model in immature rats. Celecoxib 27-36 toll-like receptor 4 Rattus norvegicus 46-50 29763644-4 2018 In this study, the drug celecoxib (CCX) was used as a blocker of the cyclooxygenase 2 (COX-2) and HMGB1/TLR-4 pathways. Celecoxib 24-33 toll-like receptor 4 Rattus norvegicus 104-109 29763644-4 2018 In this study, the drug celecoxib (CCX) was used as a blocker of the cyclooxygenase 2 (COX-2) and HMGB1/TLR-4 pathways. Celecoxib 35-38 toll-like receptor 4 Rattus norvegicus 104-109 29763644-8 2018 When the CCX group was compared to the KA group, there was also a significant decrease in the number of HMGB1 and TLR-4 transcripts (p < 0.05) and in COX-2 protein expression (p < 0.05) in the most important areas for seizure generation (the hippocampus and cortex) at both the early and late time points. Celecoxib 9-12 toll-like receptor 4 Rattus norvegicus 114-119