PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28466254-0 2017 Celecoxib Alleviates Memory Deficits by Downregulation of COX-2 Expression and Upregulation of the BDNF-TrkB Signaling Pathway in a Diabetic Rat Model. Celecoxib 0-9 neurotrophic receptor tyrosine kinase 2 Rattus norvegicus 104-108 28466254-12 2017 We found that brain-derived neurotrophic factor (BDNF) and phosphorylated tropomyosin-related kinase (p-TrkB) were decreased in diabetic rats but were effectively reversed by celecoxib treatment. Celecoxib 175-184 neurotrophic receptor tyrosine kinase 2 Rattus norvegicus 104-108 28466254-14 2017 The present findings provide novel data that celecoxib reverses memory deficits via probable downregulation of hippocampal COX-2 expression and upregulation of the BDNF-TrkB signaling pathway in a diabetic rat. Celecoxib 45-54 neurotrophic receptor tyrosine kinase 2 Rattus norvegicus 169-173