PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20630498-0	2010	IL-17A stimulates the expression of inflammatory cytokines via celecoxib-blocked prostaglandin in MC3T3-E1 cells.	Celecoxib	63-72	interleukin 17A	Mus musculus	0-6	
35159480-6	2022	MES and celecoxib reduced the inflammation level of colon tissue, as indicated by its suppression on a panel of pro-inflammatory cytokines, including interleukin (IL)-1beta, IL-17, tumor necrosis factor alpha, and interferon gamma, and a group of inflammatory proteins, including intracellular adhesion molecule 1, vascular adhesion molecule 1, matrix metalloproteinase (MMP)-2, MMP-9, MMP-13, and inducible nitric oxidase.	Celecoxib	8-17	interleukin 17A	Mus musculus	174-179	
28433514-7	2017	Interestingly, recruitment of CD4+T cells and F4/80+ macrophages as well as BMSC transplantation induced up-regulation of Cox-2 and IL-17A gene expression levels were reverted by celecoxib administration.	Celecoxib	179-188	interleukin 17A	Mus musculus	132-138	
28433514-9	2017	Conditioned media of rIL-17 treated J774.2 cells when supplemented to BMSCs depicted a dose-dependent increase in the number of apoptotic cells and proapoptotic protein expression that was perturbed by celecoxib or IL-17 neutralizing antibody.	Celecoxib	202-211	interleukin 17A	Mus musculus	22-27	
28433514-11	2017	CONCLUSION: Celecoxib protects transplanted BMSCs from Cox-2/IL-17-induced inflammation and increases their engraftment, differentiation into keratinocytes and re-epithelialization thereby potentiating wound tissue repair.	Celecoxib	12-21	interleukin 17A	Mus musculus	61-66	
20937352-0	2011	Interleukin-17A induces cathepsin K and MMP-9 expression in osteoclasts via celecoxib-blocked prostaglandin E2 in osteoblasts.	Celecoxib	76-85	interleukin 17A	Mus musculus	0-15	
20937352-9	2011	Celecoxib, a specific inhibitor of cyclooxygenase-2 (COX-2), blocked both the IL-17A-stimulated increase in TRAP-positive multinucleated cells and the expression of cathepsin K and MMP-9.	Celecoxib	0-9	interleukin 17A	Mus musculus	78-84	
20937352-11	2011	These results suggest that IL-17A induces the differentiation and function of osteoclasts via celecoxib-blocked prostaglandin, mainly PGE(2), in osteoblasts.	Celecoxib	94-103	interleukin 17A	Mus musculus	27-33	
20630498-11	2010	CONCLUSION: These results suggest that IL-17A stimulates the expression of bone resorption-related inflammatory cytokines through an autocrine mechanism involving celecoxib-blocked PGs, mainly PGE(2), in osteoblasts.	Celecoxib	163-172	interleukin 17A	Mus musculus	39-45	
20630498-8	2010	Celecoxib blocked the stimulatory effect of IL-17A on the expression of COX-2, IL-1alpha, IL-6, IL-8, and IL-11 as well as PGE(2) production, whereas it did not block TNF-alpha expression.	Celecoxib	0-9	interleukin 17A	Mus musculus	44-50