PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12376657-8	2002	These results substantiate the existence of a new subpathway (22-OHCR --> 22-OH-4-en-3-one --> 22-OH-3-one --> 6-deoxoCT) and reveal that the det2 mutant is defective in the conversion of 22-OH-4-en-3-one to 22-OH-3-one, which leads to brassinolide biosynthesis.	brassinolide	245-257	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	151-155	
8602526-3	1996	A mutation of glutamate 204, which is absolutely required for the activity of human steroid reductase, abolishes the in vivo activity of DET2 and leads to defects in light-regulated development that can be ameliorated by application of a plant steroid, brassinolide.	brassinolide	253-265	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	137-141	
11867704-4	2002	Treatment of the det2 mutants with the brassinosteroid, brassinolide, reversed the mutation and restored the potential for growth to that of the wild type.	brassinolide	56-68	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	17-21	
8602526-4	1996	Thus, DET2 may encode a reductase in the brassinolide biosynthetic pathway, and brassinosteroids may constitute a distinct class of phytohormones with an important role in light-regulated development of higher plants.	brassinolide	41-53	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	6-10