PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15044630-0	2004	Cultured rat microglial cells synthesize the endocannabinoid 2-arachidonylglycerol, which increases proliferation via a CB2 receptor-dependent mechanism.	glyceryl 2-arachidonate	61-82	cannabinoid receptor 2	Rattus norvegicus	120-123	
15013854-1	2004	2-Arachidonoylglycerol (2-AG) is an endogenous cannabinoid that binds to CB1 and CB2 cannabinoid receptors, inducing cannabimimetic effects.	glyceryl 2-arachidonate	0-22	cannabinoid receptor 2	Rattus norvegicus	81-84	
15013854-1	2004	2-Arachidonoylglycerol (2-AG) is an endogenous cannabinoid that binds to CB1 and CB2 cannabinoid receptors, inducing cannabimimetic effects.	glyceryl 2-arachidonate	24-28	cannabinoid receptor 2	Rattus norvegicus	81-84	
15044630-8	2004	The CB(2) receptor in untreated cells is expressed both at the cell surface and internally, and exposure of the cells to 2-AG significantly increases receptor internalization.	glyceryl 2-arachidonate	121-125	cannabinoid receptor 2	Rattus norvegicus	4-18	
17179944-0	2007	The antinociceptive effects of intraplantar injections of 2-arachidonoyl glycerol are mediated by cannabinoid CB2 receptors.	glyceryl 2-arachidonate	58-81	cannabinoid receptor 2	Rattus norvegicus	110-113	
16678907-5	2006	The results of structure-activity relationship studies suggested that 2-AG rather than anandamide is the true natural ligand for both the CB1 and the CB2 receptors.	glyceryl 2-arachidonate	70-74	cannabinoid receptor 2	Rattus norvegicus	150-153	
34074811-8	2022	The facilitation of 2-AG signaling in the dlPAG reduced contextual fear expression and exhibited an anxiolytic-like effect in the VCT in a mechanism dependent on activation of CB1 and CB2.	glyceryl 2-arachidonate	20-24	cannabinoid receptor 2	Rattus norvegicus	184-187	
34074811-11	2022	In conclusion, we confirmed the anti-aversive properties of 2-AG in the dlPAG through CB1 and CB2 mechanisms.	glyceryl 2-arachidonate	60-64	cannabinoid receptor 2	Rattus norvegicus	94-97	
29896156-10	2018	Indeed, in vitro-incubated testis show that AEA-CB2 activity affects negatively monoacylglycerol-lipase levels via upregulation of CB1 suggesting a CB1/CB2-mediated relationship between AEA and 2-AG.	glyceryl 2-arachidonate	194-198	cannabinoid receptor 2	Rattus norvegicus	48-51	
33450278-11	2021	2-AG activation of both CB1 and CB2 receptors and the PI3K/Akt downstream signaling pathway, as substantiated by the use of Akt2-/-mice, afforded neuroprotection against AMPA excitotoxicity.	glyceryl 2-arachidonate	0-4	cannabinoid receptor 2	Rattus norvegicus	32-35	
32375160-11	2020	The results suggest that JZL184 attenuates the behavioral consequences of predator stress through a mechanism that requires 2-AG-mediated activation of CB2 receptors, whose transcription may be induced by the stress itself.	glyceryl 2-arachidonate	124-128	cannabinoid receptor 2	Rattus norvegicus	152-155	
31967664-9	2020	CONCLUSIONS AND IMPLICATIONS: These results suggest that a MGL substrate in the ACC, likely 2-AG, modulates FCA, and that within the ACC, 2-AG-CB2 receptor signalling may suppress this form of endogenous analgesia.	glyceryl 2-arachidonate	138-142	cannabinoid receptor 2	Rattus norvegicus	143-146	
29842858-5	2018	Pharmacological enhancement of 2-AG tone facilitated memory consolidation through activation of CB2 receptor signaling.	glyceryl 2-arachidonate	31-35	cannabinoid receptor 2	Rattus norvegicus	96-99	
29896156-10	2018	Indeed, in vitro-incubated testis show that AEA-CB2 activity affects negatively monoacylglycerol-lipase levels via upregulation of CB1 suggesting a CB1/CB2-mediated relationship between AEA and 2-AG.	glyceryl 2-arachidonate	194-198	cannabinoid receptor 2	Rattus norvegicus	152-155	
24671573-2	2014	In the present study, we show that the application of the endocannabinoids (eCBs) 2-arachidonoylglycerol (2-AG) and methanandamide [a stable analog of the eCB anandamide (AEA)] can activate CB2Rs of mPFC layer II/III pyramidal neurons, which subsequently induces a Cl(-) current.	glyceryl 2-arachidonate	82-104	cannabinoid receptor 2	Rattus norvegicus	190-193	
26621126-7	2016	Moreover, even though CB2 receptors (CB2Rs) were expressed in rat Muller cells, the effects of WIN55212-2 and 2-AG on Ca(2+) channel currents were not blocked by AM630, a selective CB2R antagonist.	glyceryl 2-arachidonate	110-114	cannabinoid receptor 2	Rattus norvegicus	22-25	
24768821-8	2014	Taken together, the results of the present study show that CB1 and/or CB2 receptor antagonists trigger a significant modulation of 2-AG metabolism, underlining their relevance as therapeutic strategy for controlling endocannabinoid levels in physiological aging.	glyceryl 2-arachidonate	131-135	cannabinoid receptor 2	Rattus norvegicus	70-73	
24136226-1	2013	The cannabinoid CB2 receptor, which is activated by the endocannabinoid 2-arachidonoyl-glycerol (2-AG), protects striatal neurons from apoptotic death caused by the local administration of malonate, a rat model of Huntington"s disease (HD).	glyceryl 2-arachidonate	72-95	cannabinoid receptor 2	Rattus norvegicus	16-28	
24136226-1	2013	The cannabinoid CB2 receptor, which is activated by the endocannabinoid 2-arachidonoyl-glycerol (2-AG), protects striatal neurons from apoptotic death caused by the local administration of malonate, a rat model of Huntington"s disease (HD).	glyceryl 2-arachidonate	97-101	cannabinoid receptor 2	Rattus norvegicus	16-28