PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17932317-0	2007	Adiponectin mediates the suppressive effect of rosiglitazone on plasminogen activator inhibitor-1 production.	Rosiglitazone	47-60	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	64-97	
21757225-3	2011	We examined the effect of the PPARgamma agonist rosiglitazone on the expression of plasminogen activator inhibitor-1 (PAI-1) that is the primary inhibitor of fibrinolysis in the liver of diabetic mice and cultured mouse and human hepatocytes.	Rosiglitazone	48-61	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	83-116	
21757225-3	2011	We examined the effect of the PPARgamma agonist rosiglitazone on the expression of plasminogen activator inhibitor-1 (PAI-1) that is the primary inhibitor of fibrinolysis in the liver of diabetic mice and cultured mouse and human hepatocytes.	Rosiglitazone	48-61	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	118-123	
21757225-5	2011	An intraperitoneal injection of rosiglitazone significantly increased plasma PAI-1 concentrations in parallel with hepatic, but not with adipose mRNA levels in db/db mice, and did not affect these parameters in wild-type mice.	Rosiglitazone	32-45	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	77-82	
21757225-6	2011	Rosiglitazone as well as the PPARalpha agonist bezafibrate significantly induced PAI-1 mRNA expression in cultured mouse hepatocytes.	Rosiglitazone	0-13	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	81-86	
17932317-2	2007	METHODS AND RESULTS: Our clinical study (n=64) showed that after 24-week add-on therapy, the rosiglitazone group had a greater mean reduction in plasma PAI-1 levels (25%, versus 12% in sulfonylurea group, P=0.002).	Rosiglitazone	93-106	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	152-157	
17932317-4	2007	Rosiglitazone (20 mg/kg/d) reduced adipose tissue PAI-1 mRNA expression and its plasma levels in wild-type C57 mice with diet-induced obesity (P<0.001), but this suppressive effect was attenuated in adiponectin knockout mice.	Rosiglitazone	0-13	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	50-55	
17932317-7	2007	CONCLUSIONS: The antithrombotic effect of rosiglitazone is mediated, at least in part, through the suppressive effect of adiponectin on PAI-1 production.	Rosiglitazone	42-55	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	136-141	
16254032-10	2006	In summary, longitudinal profiling of multiple plasma analytes identified PAI-1 as a useful biomarker to monitor for differential pharmacogenetic responses to Rosi in these new mouse models of T2D.	Rosiglitazone	159-163	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	74-79	
34097888-10	2021	Although all the studied compounds influenced the expression of Dlk1, Fabp4, Vegfa, Pai-1, Resistin, Adiponectin, and Ppargamma genes, none of them caused gene expression similar to that induced by rosiglitazone or pioglitazone.	Rosiglitazone	198-211	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	84-89