PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17909895-0	2007	The peroxisome proliferator activated receptor gamma (PPARgamma) ligand rosiglitazone modulates bronchoalveolar lavage levels of leptin, adiponectin, and inflammatory cytokines in lean and obese mice.	Rosiglitazone	72-85	leptin	Mus musculus	129-135	
17909895-7	2007	Rosiglitazone treatment lowered leptin levels in lean mice, but increased leptin levels in BAL fluid of obese mice (p < 0.01).	Rosiglitazone	0-13	leptin	Mus musculus	32-38	
17909895-7	2007	Rosiglitazone treatment lowered leptin levels in lean mice, but increased leptin levels in BAL fluid of obese mice (p < 0.01).	Rosiglitazone	0-13	leptin	Mus musculus	74-80	
12923776-0	2003	Effect of rosiglitazone on the differential expression of obesity and insulin resistance associated proteins in lep/lep mice.	Rosiglitazone	10-23	leptin	Mus musculus	112-115	
12923776-0	2003	Effect of rosiglitazone on the differential expression of obesity and insulin resistance associated proteins in lep/lep mice.	Rosiglitazone	10-23	leptin	Mus musculus	116-119	
12923776-6	2003	Rosiglitazone normalized the impaired glucose tolerance and dyslipidemia in lep/lep mice but had no significant effect in the lean mice.	Rosiglitazone	0-13	leptin	Mus musculus	76-79	
12923776-8	2003	Thirty-four polypeptides were differentially expressed (p < 0.05) between lep/lep and lean mice and eleven were significantly (p < 0.05) modulated by rosiglitazone treatment of the obese mice.	Rosiglitazone	156-169	leptin	Mus musculus	77-80	
12923776-8	2003	Thirty-four polypeptides were differentially expressed (p < 0.05) between lep/lep and lean mice and eleven were significantly (p < 0.05) modulated by rosiglitazone treatment of the obese mice.	Rosiglitazone	156-169	leptin	Mus musculus	81-84	
18790715-0	2008	Leptin inhibits rosiglitazone-induced adipogenesis in murine primary adipocytes.	Rosiglitazone	16-29	leptin	Mus musculus	0-6	
18790715-3	2008	In this study, the effects of leptin on rosiglitazone-induced adipocyte differentiation were investigated in the primary preadipocytes prepared from subcutaneous fat tissues of C57BL/6-Lep(ob/ob) mouse.	Rosiglitazone	40-53	leptin	Mus musculus	30-36	
18790715-4	2008	We found that acute and prolonged treatment of leptin on preadipocytes inhibited the rosiglitazone-induced transcription factor expression and adipocyte differentiation, respectively, accompanied with decreased expression of PPARgamma and aP2.	Rosiglitazone	85-98	leptin	Mus musculus	47-53	
18790715-7	2008	Taken together, these data suggest that leptin has a direct inhibitory effect on the rosiglitazone-induced adipocyte differentiation and PPARgamma expression, in which ERK1/2 MAP kinase and JAK/STAT1 signaling pathways are involved.	Rosiglitazone	85-98	leptin	Mus musculus	40-46	
12239279-9	2002	Rosiglitazone increased carboxypeptidase B expression in both lep/lep and normal mice suggesting that this might be an independent effect of rosiglitazone that contributes to improved insulin processing.	Rosiglitazone	0-13	leptin	Mus musculus	62-65	
12239279-9	2002	Rosiglitazone increased carboxypeptidase B expression in both lep/lep and normal mice suggesting that this might be an independent effect of rosiglitazone that contributes to improved insulin processing.	Rosiglitazone	0-13	leptin	Mus musculus	66-69	
30463649-13	2018	Rosiglitazone significantly promoted the expression of adiponectin and inhibited the expression of leptin in mesenteric adipocytes.	Rosiglitazone	0-13	leptin	Mus musculus	99-105	
21723971-7	2012	Administration of antidiabetic TZD rosiglitazone, which sensitizes cells to insulin and increases adipocyte metabolic functions, significantly increased both, BAT (UCP1, PGC1alpha, Dio2, beta3AR, Prdm16, and FoxC2) and WAT (adiponectin and leptin) gene expression in marrow of normoglycemic C57BL/6 mice, but failed to increase the expression of BAT, but not WAT, gene markers in diabetic mice.	Rosiglitazone	35-48	leptin	Mus musculus	240-246	
21352814-0	2011	Inhibitory effect of leptin on rosiglitazone-induced differentiation of primary adipocytes prepared from TallyHO/Jng mice.	Rosiglitazone	31-44	leptin	Mus musculus	21-27	
21352814-2	2011	The treatment of leptin inhibited the rosiglitazone-induced adipocyte differentiation with a decreased expression of peroxisome proliferator-activated receptor gamma (PPARgamma) a key adipogenic transcription factor, both in mRNA and protein levels.	Rosiglitazone	38-51	leptin	Mus musculus	17-23