PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24865672-5 2014 MS and Rosi prevented H2O2-induced ROS generation in A549 epithelial cells through PPAR-gamma translocation, avoiding inflammatory mediator expression via inhibiting nuclear factor (NF)-kappaB translocation. Rosiglitazone 7-11 nuclear factor kappa B subunit 1 Homo sapiens 166-192 22910418-8 2012 Consistent with the down-regulation of nuclear factor kappaB (NFkappaB) phosphorylation by rosiglitazone at the incisional sites, the number of F4/80(+)iNOS(+) M1 macrophages was decreased whereas numbers of F4/80(+)CD206(+) M2 macrophages were increased in rosiglitazone-treated incisional sites 24 h after the procedure. Rosiglitazone 91-104 nuclear factor kappa B subunit 1 Homo sapiens 39-60 22910418-8 2012 Consistent with the down-regulation of nuclear factor kappaB (NFkappaB) phosphorylation by rosiglitazone at the incisional sites, the number of F4/80(+)iNOS(+) M1 macrophages was decreased whereas numbers of F4/80(+)CD206(+) M2 macrophages were increased in rosiglitazone-treated incisional sites 24 h after the procedure. Rosiglitazone 91-104 nuclear factor kappa B subunit 1 Homo sapiens 62-70 21483233-9 2012 Rosiglitazone significantly blocks TNF-alpha-induced PTP-1B upregulation and NF-kappaB activation. Rosiglitazone 0-13 nuclear factor kappa B subunit 1 Homo sapiens 77-86 21483233-10 2012 Our data strongly suggest that TNF-alpha-induced PTP-1B overexpression may contribute to hepatic IR in obesity and diabetes, and NF-kappaB is involved in rosiglitazone attenuated PTP- 1B upregulation by TNF-alpha. Rosiglitazone 154-167 nuclear factor kappa B subunit 1 Homo sapiens 129-138 22321707-17 2011 PPAR-gamma protein was translocated from cytoplasm into nucleus and NF-kappaB protein was translocated from nucleus into cytoplasm in the rosiglitazone group. Rosiglitazone 138-151 nuclear factor kappa B subunit 1 Homo sapiens 68-77 22321707-21 2011 PPAR-gamma agonist rosiglitazone inhibited inflammation in COPD through upregulating the expression and activity of PPAR-gamma and inhibition of NF-kappaB and TNF-alpha. Rosiglitazone 19-32 nuclear factor kappa B subunit 1 Homo sapiens 145-154 20622120-7 2010 Chromatin immunoprecipitation assays demonstrated that hypoxia increased binding of the NF-kappaB subunit, p65, to the Nox4 promoter and that binding was attenuated by rosiglitazone treatment. Rosiglitazone 168-181 nuclear factor kappa B subunit 1 Homo sapiens 88-97 19417127-5 2009 Furthermore, PPARgamma activation by rosiglitazone strongly suppresses cytokine-induced transcript levels of the NF-kappaB-dependent genes intracellular adhesion molecule 1 (ICAM-1) and CXCL1 (KC), the murine homolog of IL-8, in myotubes. Rosiglitazone 37-50 nuclear factor kappa B subunit 1 Homo sapiens 113-122 18711692-5 2008 Co-incubation of proximal tubular epithelial cells with rosiglitazone significantly reduced angiotensin II and advanced glycation end product-mediated generation of reactive oxygen species, angiotensin II-dependent advanced glycation end product formation, NF-kappaB activation, and NF-kappaB-dependent pro inflammatory gene expression. Rosiglitazone 56-69 nuclear factor kappa B subunit 1 Homo sapiens 257-266 18711692-5 2008 Co-incubation of proximal tubular epithelial cells with rosiglitazone significantly reduced angiotensin II and advanced glycation end product-mediated generation of reactive oxygen species, angiotensin II-dependent advanced glycation end product formation, NF-kappaB activation, and NF-kappaB-dependent pro inflammatory gene expression. Rosiglitazone 56-69 nuclear factor kappa B subunit 1 Homo sapiens 283-292 18496506-4 2008 The activation of NF kappaB and TNF-alpha synthesis induced by polymeric IgA or TNF-alpha were downregulated by BMP-7 or rosiglitazone. Rosiglitazone 121-134 nuclear factor kappa B subunit 1 Homo sapiens 18-27 18819888-0 2008 [Effect of rosiglitazone on tumor necrosis factor-alpha-induced nuclear factor-kappaB and coupling factor 6 expressions in human umbilical vein endothelial cells]. Rosiglitazone 11-24 nuclear factor kappa B subunit 1 Homo sapiens 64-85 18819888-1 2008 OBJECTIVE: To investigate the effect of rosiglitazone on the expression of nuclear factor-kappaB (NF-kappaB) and coupling factor 6 (CF6) induced by tumor necrosis factor-alpha (TNF-alpha) in cultured human umbilical vein endothelial cells (HUVEC). Rosiglitazone 40-53 nuclear factor kappa B subunit 1 Homo sapiens 75-96 18819888-1 2008 OBJECTIVE: To investigate the effect of rosiglitazone on the expression of nuclear factor-kappaB (NF-kappaB) and coupling factor 6 (CF6) induced by tumor necrosis factor-alpha (TNF-alpha) in cultured human umbilical vein endothelial cells (HUVEC). Rosiglitazone 40-53 nuclear factor kappa B subunit 1 Homo sapiens 98-107 18819888-7 2008 ROS can inhibit the activation of IKK, block NF-kappaB signaling pathway and inhibit the expression of CF6, which may be the mechanism underlying the action of TZDs on hypertension. Rosiglitazone 0-3 nuclear factor kappa B subunit 1 Homo sapiens 45-54 16728429-6 2006 The effect of rosiglitazone on nuclear factor (NF)-kappaB activity and on viability was examined using cultured human kidney (HK-2) cells. Rosiglitazone 14-27 nuclear factor kappa B subunit 1 Homo sapiens 31-57 17074107-12 2006 Rosiglitazone alleviate colonic inflammation probably the through blockade of NF-kappaB, which can be a novel approach to the ulcerative colitis treatment. Rosiglitazone 0-13 nuclear factor kappa B subunit 1 Homo sapiens 78-87 15821150-10 2005 IL-1beta-induced nuclear factor-kappaB (NF-kappaB) DNA binding activity was significantly inhibited by 15d-PGJ(2) (10 microM) and GW501516 (1 microM) but increased with 10 microM rosiglitazone. Rosiglitazone 179-192 nuclear factor kappa B subunit 1 Homo sapiens 40-49 12667961-9 2003 The NF-kappaB activation caused by CRP was inhibited by 15-deoxy-12,14-prostaglandin J2 and the PPARgamma activators, rosiglitazone and pioglitazone. Rosiglitazone 118-131 nuclear factor kappa B subunit 1 Homo sapiens 4-13 34392099-6 2021 The resultant xECM-RSG complex, enabling RSG to be delivered sequentially and continuously to cells without obvious systemic side effects, is recognized as "self" to escape immune monitoring in local immunoregulation by downregulating the expression of proinflammatory NOS2+ M1 macrophages and oxygen species (ROS) through suppressing NF-kappaB expression, greatly facilitating the regeneration of enthesis anchoring between the transplanted xenograft and host in both heterotopic and orthotopic models. Rosiglitazone 41-44 nuclear factor kappa B subunit 1 Homo sapiens 335-344 30765769-0 2019 Rosiglitazone blocks first trimester in-vitro placental injury caused by NF-kappaB-mediated inflammation. Rosiglitazone 0-13 nuclear factor kappa B subunit 1 Homo sapiens 73-82 30765769-8 2019 Lastly, markers of trophoblast differentiation and invasion reverted to control levels upon activation of PPARgamma and concomitant inhibition of NF-kappaB (either by Rosiglitazone or NF-kappaB specific inhibitor), revealing a new role for NF-kappaB in trophoblast invasion. Rosiglitazone 167-180 nuclear factor kappa B subunit 1 Homo sapiens 146-155 30765769-10 2019 The ability to reverse trophoblast-associated inflammation with Rosiglitazone offers promise that the PPARgamma - NF-kappaB pathway could one day provide a therapeutic target for placental dysfunction associated with both inflammation and abnormal trophoblast differentiation. Rosiglitazone 64-77 nuclear factor kappa B subunit 1 Homo sapiens 114-123