PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22315431-6 2012 Consequently, FGF21 deletion prevents the deleterious bone loss side effect of the PPAR-gamma agonist rosiglitazone. Rosiglitazone 102-115 fibroblast growth factor 21 Homo sapiens 14-19 21720023-8 2011 Our findings suggest that PPARgamma-activating antidiabetic drugs such as rosiglitazone and pioglitazone induce FGF21 expression in mouse and human hepatocytes, and that PPARgamma rather than PPARalpha might play an important role in human FGF21 production. Rosiglitazone 74-87 fibroblast growth factor 21 Homo sapiens 240-245 19528204-0 2009 Effects of rosiglitazone on fasting plasma fibroblast growth factor-21 levels in patients with type 2 diabetes mellitus. Rosiglitazone 11-24 fibroblast growth factor 21 Homo sapiens 43-70 19528204-2 2009 This study aimed to investigate the effects of rosiglitazone on plasma FGF-21 levels in patients with type 2 diabetes mellitus (T2DM). Rosiglitazone 47-60 fibroblast growth factor 21 Homo sapiens 71-77 19528204-8 2009 Fasting plasma FGF-21 levels were decreased significantly in pT2DM group after the treatment with rosiglitazone compared with pre-treatment (1.59+/-0.63 vs 1.87+/-0.64 micro/l, P<0.05). Rosiglitazone 98-111 fibroblast growth factor 21 Homo sapiens 15-21 19528204-10 2009 CONCLUSIONS: In pT2DM patients, plasma FGF-21 levels are increased, but significantly decreased after the treatment with rosiglitazone on top of ongoing metformin therapy. Rosiglitazone 121-134 fibroblast growth factor 21 Homo sapiens 39-45 19528204-11 2009 These data suggest that rosiglitazone may play a role in lowering FGF-21 levels in T2DM patients. Rosiglitazone 24-37 fibroblast growth factor 21 Homo sapiens 66-72 17063460-5 2007 Moreover, chronic activation of the PPARgamma pathway in 3T3-L1 adipocytes with the PPARgamma agonist and anti-diabetic agent, rosiglitazone (BRL 49653), enhances FGF-21 action to induce tyrosine phosphorylation of FGF receptor-2. Rosiglitazone 127-140 fibroblast growth factor 21 Homo sapiens 163-169