PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31252559-5 2019 Furthermore, a strong reduction of the hexokinase II (HKII), phosphorylated form of PKM2 (at Tyr105 and Ser37) and lactate dehydrogenase A (LDH-A) was observed in response to imatinib along with a strong upregulation of mitochondrial complexes (OXPHOS). Imatinib Mesylate 175-183 hexokinase 2 Homo sapiens 39-52 31252559-5 2019 Furthermore, a strong reduction of the hexokinase II (HKII), phosphorylated form of PKM2 (at Tyr105 and Ser37) and lactate dehydrogenase A (LDH-A) was observed in response to imatinib along with a strong upregulation of mitochondrial complexes (OXPHOS). Imatinib Mesylate 175-183 hexokinase 2 Homo sapiens 54-58 29559564-10 2018 Overexpression of miR-202 sensitized imatinib resistant CML through the miR-202-mediated glycolysis inhibition by targetting HK2. Imatinib Mesylate 37-45 hexokinase 2 Homo sapiens 125-128 34738628-7 2022 The expression of glycolysis-related molecules (GLUT-1, hexokinase 2, pyruvate kinase M2 and lactate dehydrogenase) was assessed in parental and imatinib-resistant cells by western blotting, reverse transcription-quantitative PCR and glucose and lactate measurement kits. Imatinib Mesylate 145-153 hexokinase 2 Homo sapiens 56-68 34738628-12 2022 Although imatinib treatment downregulated GLUT-1 expression and other glycolysis pathway components hexokinase 2, pyruvate kinase M2, and lactate dehydrogenase in parental GIST-T1 cells even at low concentrations. Imatinib Mesylate 9-17 hexokinase 2 Homo sapiens 100-112 29559564-0 2018 Overexpression of miR-202 resensitizes imatinib resistant chronic myeloid leukemia cells through targetting Hexokinase 2. Imatinib Mesylate 39-47 hexokinase 2 Homo sapiens 108-120