PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26394716-0 2016 Arabinoxylan activates Dectin-1 and modulates particulate beta-glucan-induced Dectin-1 activation. arabinoxylan 0-12 C-type lectin domain containing 7A Homo sapiens 23-31 26394716-0 2016 Arabinoxylan activates Dectin-1 and modulates particulate beta-glucan-induced Dectin-1 activation. arabinoxylan 0-12 C-type lectin domain containing 7A Homo sapiens 78-86 26394716-3 2016 METHODS AND RESULTS: By applying reporter cell lines for Toll-like receptors (TLRs) and Dectin-1, we demonstrated that arabinoxylan interacts with Dectin-1 receptors and not with TLRs. arabinoxylan 119-131 C-type lectin domain containing 7A Homo sapiens 88-96 26394716-3 2016 METHODS AND RESULTS: By applying reporter cell lines for Toll-like receptors (TLRs) and Dectin-1, we demonstrated that arabinoxylan interacts with Dectin-1 receptors and not with TLRs. arabinoxylan 119-131 C-type lectin domain containing 7A Homo sapiens 147-155 26394716-4 2016 Arabinoxylan activates Dectin-1 to a similar magnitude as soluble beta-glucans. arabinoxylan 0-12 C-type lectin domain containing 7A Homo sapiens 23-31 26394716-6 2016 As arabinoxylan is also soluble, the inhibiting capacity of arabinoxylan on particulate beta-glucan-activated Dectin-1 cell lines was studied. arabinoxylan 60-72 C-type lectin domain containing 7A Homo sapiens 110-118 26394716-8 2016 The Dectin-1 inhibitory function of arabinoxylan was further confirmed in human dendritic cells that demonstrated reduced production of IL-10 and TNF-alpha. arabinoxylan 36-48 C-type lectin domain containing 7A Homo sapiens 4-12 26394716-11 2016 CONCLUSION: Arabinoxylan activates Dectin-1 and supports antifungal immune responses in human dendritic cells. arabinoxylan 12-24 C-type lectin domain containing 7A Homo sapiens 35-43 35447262-7 2022 Using a Dectin-1 antagonist or a CR3 antibody, it was demonstrated that arabinoxylan-induced trained immunity in macrophages is mainly dependent on Dectin-1b. arabinoxylan 72-84 C-type lectin domain containing 7A Homo sapiens 8-16