PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25943894-5 2015 In activated cells, anandamide (AEA), acting as an immune-modulator, suppresses Tat B effect through MKP-1 but Tat C action via MEK-1. aea 32-35 dual specificity phosphatase 1 Homo sapiens 101-106 16387640-4 2006 In this study, we show that the endocannabinoid system is highly activated during CNS inflammation and that the endocannabinoid anandamide (AEA) protects neurons from inflammatory damage by CB(1/2) receptor-mediated rapid induction of mitogen-activated protein kinase phosphatase-1 (MKP-1) in microglial cells associated with histone H3 phoshorylation of the mkp-1 gene sequence. aea 140-143 dual specificity phosphatase 1 Homo sapiens 235-281 16387640-4 2006 In this study, we show that the endocannabinoid system is highly activated during CNS inflammation and that the endocannabinoid anandamide (AEA) protects neurons from inflammatory damage by CB(1/2) receptor-mediated rapid induction of mitogen-activated protein kinase phosphatase-1 (MKP-1) in microglial cells associated with histone H3 phoshorylation of the mkp-1 gene sequence. aea 140-143 dual specificity phosphatase 1 Homo sapiens 283-288 16387640-4 2006 In this study, we show that the endocannabinoid system is highly activated during CNS inflammation and that the endocannabinoid anandamide (AEA) protects neurons from inflammatory damage by CB(1/2) receptor-mediated rapid induction of mitogen-activated protein kinase phosphatase-1 (MKP-1) in microglial cells associated with histone H3 phoshorylation of the mkp-1 gene sequence. aea 140-143 dual specificity phosphatase 1 Homo sapiens 359-364 16387640-5 2006 As a result, AEA-induced rapid MKP-1 expression switches off MAPK signal transduction in microglial cells activated by stimulation of pattern recognition receptors. aea 13-16 dual specificity phosphatase 1 Homo sapiens 31-36