PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14725899-8	2004	The PI3 kinase inhibitors LY294002 and wortmannin substituted for G-CSF in combination with IL-3 since proliferation in the presence of LY294002/wortmannin+IL-3 was enhanced to the same extent as in the presence of G-CSF+IL-3.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	26-34	interleukin 3	Homo sapiens	92-96	
19656152-3	2009	The PI-3K pathway promoted differentiation of interleukin-3 (IL-3)-stimulated myelopoiesis via Akt, because inhibition of the PI-3K/Akt pathway with LY294002 or SH-5 increased proliferation.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	149-157	interleukin 3	Homo sapiens	46-59	
19656152-3	2009	The PI-3K pathway promoted differentiation of interleukin-3 (IL-3)-stimulated myelopoiesis via Akt, because inhibition of the PI-3K/Akt pathway with LY294002 or SH-5 increased proliferation.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	149-157	interleukin 3	Homo sapiens	61-65	
17624239-10	2007	The PI3-kinase inhibitors, wortmannin and LY294002 counteracted the IL-3-induced expression of CD203c, whereas MEK- and PKC inhibitors showed no effects.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	42-50	interleukin 3	Homo sapiens	68-72	
14725899-8	2004	The PI3 kinase inhibitors LY294002 and wortmannin substituted for G-CSF in combination with IL-3 since proliferation in the presence of LY294002/wortmannin+IL-3 was enhanced to the same extent as in the presence of G-CSF+IL-3.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	26-34	interleukin 3	Homo sapiens	156-160	
14725899-8	2004	The PI3 kinase inhibitors LY294002 and wortmannin substituted for G-CSF in combination with IL-3 since proliferation in the presence of LY294002/wortmannin+IL-3 was enhanced to the same extent as in the presence of G-CSF+IL-3.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	26-34	interleukin 3	Homo sapiens	156-160	
14725899-8	2004	The PI3 kinase inhibitors LY294002 and wortmannin substituted for G-CSF in combination with IL-3 since proliferation in the presence of LY294002/wortmannin+IL-3 was enhanced to the same extent as in the presence of G-CSF+IL-3.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	136-144	interleukin 3	Homo sapiens	92-96	
14725899-9	2004	In contrast, LY294002 and wortmannin inhibited proliferation in the presence of EPO and in the presence of EPO+IL-3.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	13-21	interleukin 3	Homo sapiens	111-115	
12554807-4	2003	The PI-3K inhibitor LY294002 specifically inhibited cell survival in the presence of the chimera, suggesting a key role of this enzyme in the potentiation of survival caused by the linkage of IGF and IL-3.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	20-28	interleukin 3	Homo sapiens	200-204	
12423306-7	2002	The effects of IL-3 on apoptosis and CD69 surface expression of human basophils were completely blocked by LY294002 (LY), a potent inhibitor of phosphatidylinositol 3-kinase (PI3-K), but only partially inhibited by lactacystin, a proteasome inhibitor that prevents degradation of IkappaB and NF-kappaB translocation.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	107-115	interleukin 3	Homo sapiens	15-19	
12384416-3	2002	The activation of Rac-1 induced by cross-linking the BCR or by IL-3 stimulation was blocked only partially by Ly294002, with about 25% to 30% of Rac-1 activation still occurring in the absence of detectable increases in phosphatidyl-inositol-3 kinase (PI-3K) activity.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	110-118	interleukin 3	Homo sapiens	63-67	
12423306-7	2002	The effects of IL-3 on apoptosis and CD69 surface expression of human basophils were completely blocked by LY294002 (LY), a potent inhibitor of phosphatidylinositol 3-kinase (PI3-K), but only partially inhibited by lactacystin, a proteasome inhibitor that prevents degradation of IkappaB and NF-kappaB translocation.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	107-109	interleukin 3	Homo sapiens	15-19	
11335710-3	2001	Expression of Deltap85 and incubation with LY294002 both inhibited IL-3-induced activation of Mek, Erk1, and Erk2.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	43-51	interleukin 3	Homo sapiens	67-71	
7492306-6	1995	Interestingly, the same effect was seen in cells in the presence of IL-3 and Steel factor, while cells incubated in the presence of granulocyte-macrophage colony stimulating factor, and to a lesser extent, IL-5 could bypass the effect of wortmannin or LY294002.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	252-260	interleukin 3	Homo sapiens	68-72