PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30074018-16 2018 However, combined SC79 and LY294002 treatment abolished SC79-induced p-Akt activity, inhibited anti-apoptotic bcl-2 and promoted anti-apoptotic Bax expression in MCAO mice. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 27-35 BCL2-associated X protein Mus musculus 144-147 20731895-7 2008 RESULTS: The tumor-inhibiting rate of paclitaxel plus LY294002 (92.47%) was significantly higher than the paclitaxel alone (65.59%)(P <0.05).The protein expression of bcl-2 in paclitaxel plus LY294002 group were significantly higher, while bax was significantly lower than that in the other two groups (P <0.05). 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 54-62 BCL2-associated X protein Mus musculus 243-246 31189740-9 2019 Moreover, overexpressed miR-613, silenced FN1 or LY294002 treatment suppressed proliferation, invasion, migration, and angiogenesis in NPC cells, which was indicated by reduced expression of AKT, mTOR, MMP-2, MMP-9, VEGF, and CD31 as well as decreased ratio of Bcl-2/Bax and increased expression of Cleaved-caspase3. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 49-57 BCL2-associated X protein Mus musculus 267-270 33678633-12 2021 Compared to the MFN-M group, cell apoptosis and the protein level of Bax in the MFN+LY294002 group were significantly increased; the Bcl-2 protein expression was significantly decreased (all P<0.05). 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 84-92 BCL2-associated X protein Mus musculus 69-72 21614693-7 2011 In comparison with the other two groups, LY294002+SN50 group exhibited more severe apoptosis, with expression of Bcl-2 decreased and that of P53 and Bax increased more significantly(P<0.05). 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 41-49 BCL2-associated X protein Mus musculus 149-152 24686182-10 2014 While, the effect of Apelin-13 on Bax, Bcl-2, caspase-3 and cleaved caspase-3 was attenuated by LY294002 and PD98059. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 96-104 BCL2-associated X protein Mus musculus 34-37 21496122-6 2011 In this study we clearly demonstrated that pre-treatment with LY294002 reversed the increased activation of eNOS and Akt observed following SCI, and developed a severe trauma characterized by oedema, tissue damage and apoptosis (measured by TUNEL staining, Bax, Bcl-2 and Fas-L expression). 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 62-70 BCL2-associated X protein Mus musculus 257-260