PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22124782-5	2012	Y-27632, a ROCK inhibitor, suppressed ICAM-1 expression and phosphorylation of MYPT-1 induced by LA.	Y 27632	0-7	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	79-85	
17105828-10	2007	This phosphorylation of MYPT1 was significantly inhibited by application of Y-27632 and by pretreatment with pertussis toxin.	Y 27632	76-83	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	24-29	
21850162-16	2011	Y-39983 was several-fold more potent when compared with Y-27632 at inhibiting the phosphorylation of MYPT1 at either Thr853 or Thr696 commensurate with its greater potency at inhibiting the activity of human ROCK-I and ROCK-II enzymes.	Y 27632	56-63	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	101-106	
18599801-11	2008	Pretreatment with the nonspecific antioxidant N-acetylcysteine and the Rho kinase inhibitors (Fasudil and Y-27632) prevented MLC and MYPT-1 phosphorylation by UFP suggesting a O(2)(.-)-mediated mechanism for PM(2.5) and UFP effects.	Y 27632	106-113	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	133-139	
18991642-6	2008	This augmented responsiveness to methacholine involves the phosphorylation of myosin phosphatase targeting protein 1 (MYPT1) via Rho-kinase, however, it is attenuated by pre-treatment with Rho-kinase inhibitors such as Y-27632 and HA-1077.	Y 27632	219-226	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	78-116	
18991642-6	2008	This augmented responsiveness to methacholine involves the phosphorylation of myosin phosphatase targeting protein 1 (MYPT1) via Rho-kinase, however, it is attenuated by pre-treatment with Rho-kinase inhibitors such as Y-27632 and HA-1077.	Y 27632	219-226	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	118-123	
16038801-4	2005	Both effects showed only a slight influence with the Rho-kinase inhibitor, Y-27632; 2) an increase in phosphorylation of MYPT1 at Thr850 associated with its accumulation in the perinuclear region and nucleus.	Y 27632	75-82	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	121-126	
16439434-8	2006	In contrast, hypoxic relaxation was preserved with further addition of the Rho kinase inhibitor Y27632 (1 mum), to attenuate thiophosphorylation of MYPT1.	Y 27632	96-102	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	148-153	
24906916-11	2014	The augmentation of contraction caused by hypoxia or cIMP was accompanied by increased phosphorylation of myosin phosphatase target subunit 1 at Thr(853), which was prevented by the ROCK inhibitor Y-27632.	Y 27632	197-204	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	106-141	
15281089-8	2004	Inhibition of Rho-kinase by Y27632 abolished ND-induced MYPT1 phosphorylation, MLC phosphorylation, and stress fiber formation.	Y 27632	28-34	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	56-61	
14709404-7	2004	The specific Rho-kinase inhibitor, Y27632, abolished MYPT1 phosphorylation, MLC phosphorylation, significantly attenuated stress fiber formation and thrombin-induced TER decrease.	Y 27632	35-41	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	53-58	
24685819-9	2014	The sustained hypoxic contraction was also accompanied with increased phosphorylation of MYPT1, which was inhibited by LY294002 and Y27632.	Y 27632	132-138	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	89-94	
24557761-7	2014	Furthermore, ethanol induced Rho/ROCK activation, as indicated by increased phosphorylation of myosin-binding subunit, which could be prevented either by BAPTA, Xestospongin C, or the specific Rho/ROCK inhibitor Y27632.	Y 27632	212-218	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	95-117