PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20177148-8 2010 LPA activated RhoA in hASCs and pretreatment with the Rho kinase inhibitor Y27632 completely abrogated the LPA-induced expression of alpha-SMA, SDF-1, and VEGF in hASCs. Y 27632 75-81 vascular endothelial growth factor A Homo sapiens 155-159 16627366-9 2006 Selective blockage of ROCK with Y27632 dose-dependently inhibited VEGF-induced venular hyperpermeability. Y 27632 32-38 vascular endothelial growth factor A Homo sapiens 66-70 20114091-9 2010 Y27632 as well as fasudil enhanced FGF-2-stimulated VEGF release and Y27632 enhanced the FGF-2-induced phosphorylation levels of SAPK/JNK also in human osteoblasts. Y 27632 0-6 vascular endothelial growth factor A Homo sapiens 52-56 18397319-6 2008 Rho is a putative downstream signal of PKCzeta, and inhibition of Rho kinase with a specific inhibitor, Y27632, decreased VEGF levels and increased TSP-1 levels. Y 27632 104-110 vascular endothelial growth factor A Homo sapiens 122-126 16627366-10 2006 Moreover, inhibition of either Rho with exoenzyme C3 or ROCK with Y-27632 attenuated VEGF-induced increases in permeability, MLC phosphorylation, and actin-stress fiber formation in CVEC monolayers. Y 27632 66-73 vascular endothelial growth factor A Homo sapiens 85-89 32297701-8 2020 Y-27632 also reversed the activation of PTEN, the inactivation/dephosphorylation of PI3K/Akt and down-regulation of VEGF. Y 27632 0-7 vascular endothelial growth factor A Homo sapiens 116-120 15247219-4 2004 In this context, the inhibition of RhoA kinase (ROCK) with Y27632 or by expression of dominant negative forms of RhoA or ROCK impaired the VEGF-induced phosphorylation of Tyr(407) within FAK. Y 27632 59-65 vascular endothelial growth factor A Homo sapiens 139-143 14704227-7 2004 Pretreatment of the cells with Rho-associated protein kinase inhibitor, Y-27632 (10 microM), partially inhibited VEGF-induced ACE upregulation. Y 27632 72-79 vascular endothelial growth factor A Homo sapiens 113-117 26825658-7 2017 A CTGF-neutralizing antibody and the ROCK inhibitor, Y-27632, abolished tensile-force-induced Vegf expression. Y 27632 53-60 vascular endothelial growth factor A Homo sapiens 94-98 26209534-7 2015 C3 exoenzyme or Y27632 inhibited the VEGF-A-induced proliferation of DJM-1 cells. Y 27632 16-22 vascular endothelial growth factor A Homo sapiens 37-43 23624342-8 2013 In addition, Rho inhibitor C3 transferase, ROCK inhibitor Y27632 or depletion of endogenous MRTF-A abolished the VEGF-induced differentiation of MSCs into ECs. Y 27632 58-64 vascular endothelial growth factor A Homo sapiens 113-117