PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35054855-5 2022 We hypothesized that BPS would impair EGF-mediated invasion and proliferation in EVTs. bis(4-hydroxyphenyl)sulfone 21-24 epidermal growth factor Homo sapiens 38-41 35054855-8 2022 We demonstrated that BPS blocked EGF-induced phosphorylation of EGFR by acting as a competitive antagonist to EGFR. bis(4-hydroxyphenyl)sulfone 21-24 epidermal growth factor Homo sapiens 33-36 35054855-9 2022 Transwell assay and a three-dimensional microfluidic chip invasion assay revealed that BPS exposure can block EGF-mediated cell invasion. bis(4-hydroxyphenyl)sulfone 87-90 epidermal growth factor Homo sapiens 110-113 35054855-10 2022 BPS also blocked EGF-mediated proliferation and endovascular differentiation. bis(4-hydroxyphenyl)sulfone 0-3 epidermal growth factor Homo sapiens 17-20 35054855-11 2022 In conclusion, BPS can prevent EGF-mediated EVT proliferation and invasion through EGFR antagonism. bis(4-hydroxyphenyl)sulfone 15-18 epidermal growth factor Homo sapiens 31-34