PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25273829-0	2015	Men with lower HDL cholesterol levels have significant increment of soluble CD40 ligand and high-sensitivity CRP levels following the cessation of long-term clopidogrel therapy.	Clopidogrel	157-168	CD40 ligand	Homo sapiens	76-87	
26156883-5	2015	Clinical evidence shows that P2Y12 inhibition by clopidogrel is associated with a reduction in platelet-related mediators of inflammation, such as soluble P-selectin and CD40L, following atherothrombosis.	Clopidogrel	49-60	CD40 ligand	Homo sapiens	170-175	
19855266-7	2010	Levels of CD62P, CD63, and CD40L were more significantly reduced in the clopidogrel group than in the aspirin group in the first week after stroke.	Clopidogrel	72-83	CD40 ligand	Homo sapiens	27-32	
24469880-8	2013	CONCLUSIONS: Increasing the dose of ASA from 75 mg to 150 mg daily or switching ASA 75 mg to clopidogrel 75 mg daily may reduce concentrations of some inflammatory markers (in particular hsCRP, IL-6 and CD40L) in T2DM patients with HPR treated previously with 75 mg of ASA.	Clopidogrel	93-104	CD40 ligand	Homo sapiens	203-208	
20069077-8	2009	Data from this study suggest that clopidogrel can decrease the expression of the CD40-ligand biomarker.	Clopidogrel	34-45	CD40 ligand	Homo sapiens	81-92	
20069077-5	2009	There was a significant difference at Week 6 in model-adjusted CD40-ligand levels in favor of clopidogrel plus aspirin compared with placebo plus aspirin in both the intent-to-treat population (difference between least-squares means = -186.5; 95% confidence interval, -342.3 to -30.8; P = 0.02) and the per-protocol population (P = 0.05).	Clopidogrel	94-105	CD40 ligand	Homo sapiens	63-74	
15487851-6	2004	Clopidogrel has additional effects on the ADP-induced expression of adhesion molecules (P-selectin, GPIIb/IIIa) and inflammatory mediators (CD40L).	Clopidogrel	0-11	CD40 ligand	Homo sapiens	140-145	
15280513-9	2004	Statins, glitazones, glycoprotein IIb/IIIa inhibitors, and clopidogrel have been demonstrated to effectively reduce CD40L levels both in vitro and in vivo.	Clopidogrel	59-70	CD40 ligand	Homo sapiens	116-121	
15019868-9	2004	Clopidogrel pretreatment was associated with lower ADP-activated platelet CD40L expression in baseline and postprocedural samples.	Clopidogrel	0-11	CD40 ligand	Homo sapiens	74-79	
14730251-7	2004	In healthy volunteers, CD40L expression in platelets is not significantly inhibited by acetylsalicylic acid (ASA) alone, but is inhibited after treatment with the ADP-receptor antagonist clopidogrel or with clopidogrel plus ASA.	Clopidogrel	187-198	CD40 ligand	Homo sapiens	23-28	
14730251-7	2004	In healthy volunteers, CD40L expression in platelets is not significantly inhibited by acetylsalicylic acid (ASA) alone, but is inhibited after treatment with the ADP-receptor antagonist clopidogrel or with clopidogrel plus ASA.	Clopidogrel	207-218	CD40 ligand	Homo sapiens	23-28	
11297035-0	2001	Platelet CD40 ligand (CD40L)--subcellular localization, regulation of expression, and inhibition by clopidogrel.	Clopidogrel	100-111	CD40 ligand	Homo sapiens	9-20	
11297035-0	2001	Platelet CD40 ligand (CD40L)--subcellular localization, regulation of expression, and inhibition by clopidogrel.	Clopidogrel	100-111	CD40 ligand	Homo sapiens	22-27	
11297035-10	2001	In contrast, clopidogrel treatment completely abolished ADP-induced expression of CD40L.	Clopidogrel	13-24	CD40 ligand	Homo sapiens	82-87