PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21094119-5 2011 Nitrite (NO(2)(-)) was found to be an uncompetitive inhibitor of heCAT activity (IC(50)=9 muM) and of CAT activity in hemolysate (IC(50)~750 muM). Nitrites 0-7 catalase Homo sapiens 67-70 23811105-6 2013 The activity of SOD and CAT decreased with the amount of nitrate and nitrite, while GSHPx and TBARS resulted unaffected. Nitrites 69-76 catalase Homo sapiens 24-27 2029741-4 1991 Sodium azide, an inhibitor of myeloperoxidase and catalase, reduced the nitrite-stimulated metabolism of BP-7,8-diol in PMA-activated leukocytes. Nitrites 72-79 catalase Homo sapiens 50-58 15214777-4 2004 Chemiluminescence detection experiments show the ability of catalase to catalyze the formation of nitrite and nitrate from hydroxyurea. Nitrites 98-105 catalase Homo sapiens 60-68 12943506-0 2003 Nitrite-catalase interaction as an important element of nitrite toxicity. Nitrites 56-63 catalase Homo sapiens 8-16 12943506-1 2003 It was established that nitrite in the presence of chloride, bromide, and thiocyanate decreases the rate of hydrogen peroxide decomposition by catalase. Nitrites 24-31 catalase Homo sapiens 143-151 12943506-4 2003 These facts suggest that nitrite induces inhibition of catalase with no change in the essence of the enzymatic process. Nitrites 25-32 catalase Homo sapiens 55-63 12943506-5 2003 Even micromolar nitrite concentrations induced a considerable decrease in catalase activity. Nitrites 16-23 catalase Homo sapiens 74-82 12943506-7 2003 In contrast, fluoride protected catalase from nitrite inhibition in the presence of the above-mentioned halides and pseudohalide. Nitrites 46-53 catalase Homo sapiens 32-40 12943506-8 2003 As hydrogen peroxide is a necessary factor for triggering a number of important toxic effects of nitrite, the latter increases its toxicity by inhibiting catalase. Nitrites 97-104 catalase Homo sapiens 154-162 12943506-10 2003 The naturally existing gradient of chloride and other anion concentrations between intra- and extracellular media appears to be the most important mechanism of cell protection from inhibition of intracellular catalase by nitrite. Nitrites 221-228 catalase Homo sapiens 209-217 11811525-8 2001 The generation of nitrite (NO2-) and nitrate (NO3-) by the NaN3/catalase/H2O2 system was maximal at pH 5.0. Nitrites 18-25 catalase Homo sapiens 64-72 8250925-0 1993 Nitrite production by stimulated human polymorphonuclear leukocytes supplemented with azide and catalase. Nitrites 0-7 catalase Homo sapiens 96-104 8250925-2 1993 We report here that nitrite production by phorbol myristate acetate (PMA)-stimulated human polymorphonuclear leukocytes (PMN) is considerably increased by the addition of azide and a further increase occurs when catalase also is added. Nitrites 20-27 catalase Homo sapiens 212-220 8250925-3 1993 Nitrite production by the PMN-PMA-azide-catalase system is unaffected by superoxide dismutase or monomethylarginine but is markedly reduced by the substitution of chronic granulomatous disease for normal neutrophils. Nitrites 0-7 catalase Homo sapiens 40-48 8250925-5 1993 These findings suggest that nitrite production does not, in this instance, reflect nitric oxide synthase activity by human neutrophils but rather the catalase-catalyzed conversion of azide to nitrite in the presence of H2O2 generated by the stimulated PMN. Nitrites 192-199 catalase Homo sapiens 150-158 28282582-4 2017 In this work the effect of nitrite on the catalytic reactions of catalase was studied. Nitrites 27-34 catalase Homo sapiens 65-73 30170003-7 2018 The results showing that NTP irradiation of the lactate solution rather than the inorganic salt solution induced the inactivation of catalase were dependent on the presence or absence of nitrite in these solutions. Nitrites 187-194 catalase Homo sapiens 133-141 28282582-0 2017 Interactions of nitrite with catalase: Enzyme activity and reaction kinetics studies. Nitrites 16-23 catalase Homo sapiens 29-37 28282582-5 2017 Catalase was inhibited by nitrite, and this process was pH-dependent. Nitrites 26-33 catalase Homo sapiens 0-8 28282582-7 2017 The presence of chloride significantly enhanced nitrite-induced catalase inhibition, in agreement with earlier observations. Nitrites 48-55 catalase Homo sapiens 64-72 28282582-8 2017 The kinetics of the reactions of nitrite with ferric catalase, its redox intermediate, Compound I, and catalase inactive form, Compound II, was also studied. Nitrites 33-40 catalase Homo sapiens 53-61 28282582-8 2017 The kinetics of the reactions of nitrite with ferric catalase, its redox intermediate, Compound I, and catalase inactive form, Compound II, was also studied. Nitrites 33-40 catalase Homo sapiens 103-111 28282582-9 2017 Possible mechanisms of nitrite-induced catalase inhibition are analyzed and the biological consequences of the reactions of catalase with nitrite are discussed. Nitrites 23-30 catalase Homo sapiens 39-47 28282582-9 2017 Possible mechanisms of nitrite-induced catalase inhibition are analyzed and the biological consequences of the reactions of catalase with nitrite are discussed. Nitrites 23-30 catalase Homo sapiens 124-132 28282582-9 2017 Possible mechanisms of nitrite-induced catalase inhibition are analyzed and the biological consequences of the reactions of catalase with nitrite are discussed. Nitrites 138-145 catalase Homo sapiens 124-132 27075937-0 2017 Nitrite and nitroso compounds can serve as specific catalase inhibitors. Nitrites 0-7 catalase Homo sapiens 52-60 27075937-1 2017 OBJECTIVE: We present evidence that nitrite and nitrosothiols, nitrosoamines and non-heme dinitrosyl iron complexes can reversibly inhibit catalase with equal effectiveness. Nitrites 36-43 catalase Homo sapiens 139-147 27075937-4 2017 It was found that chloride and bromide in concentration above 80 mM and thiocyanate in concentration above 20 muM enhance catalase inhibition by nitrite and the nitroso compounds more than 100 times. Nitrites 145-152 catalase Homo sapiens 122-130 27075937-9 2017 It is probable that a comparatively low chloride concentration in many cells is the main factor to protect catalase from inhibition by nitrite and nitroso compounds. Nitrites 135-142 catalase Homo sapiens 107-115